The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen+13 more
wiley +1 more source
Direction Of Hepatitis Supported Research At Namru-2 [PDF]
Titik berat penelitian hepatitis di NAMRU-2 pada saat ini adalah: I) penelitian binatang untuk mengetahui populasi reservoar HEV; 2) penggunaan model hewan untuk lebih diketahuinya transmisi HEV pada populasi reservoar yang dicurigai; 3) diketahuinya ...
Corwin, A. L. (Andrew)+8 more
core
Short and long term outcome of kidney transplanted patients with chronic viral hepatitis B and C
Introduction. Liver disease related to chronic viral hepatitis is a major cause of morbidity and mortality in renal transplant patients. There is no agreement upon the influence of chronic hepatitis B (HBV) and hepatitis C (HCV) infection in patient and ...
Ezequiel Ridruejo+7 more
doaj
An Atypical Presentation of Hepatitis E in Pregnancy
Hepatitis E is water born disease and transmitted by feco-oral route and it is an emerging infectious agent causing acute viral hepatitis all over the world. During pregnancy, especially in the third trimester, hepatitis E infection is characterized by a
Debkalyan Maji+3 more
doaj +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
Introduction In low-income countries, Hepatitis E infection is a common cause of acute hepatitis. So far, only two recombinant vaccines (rHEV and HEV 239) have been developed against Hepatitis E virus (HEV).
Tauseef Ahmad+5 more
doaj +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source
Association of mutations in the basal core promoter and pre-core regions of the hepatitis B viral genome and longitudinal changes in HBV level in HBEAG negative individuals: Results from a cohort study in northern Iran [PDF]
Background: Although certain HBV mutations are known to affect the expression of Hepatitis e antigen, their association with HBV viral level or clinical outcomes is less clear.
Besharat, S.+7 more
core +1 more source
A retrospective clinical and epidemiological analysis of cases of hepatitis E in St. Petersburg
Hepatitis E – zoonotic disease that has received a nosological independence twenty years ago, when Russian scientist, Professor M.S. Balayan, identified the pathogen (hepatitis E).
H. D. Peradze+3 more
doaj +1 more source