Results 51 to 60 of about 416,441 (313)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Comprehensive Evaluation of Hepatitis E Serology and Molecular Testing in a Large Cohort

Pathogens, 2020
Introduction: Reliable and cost-effective diagnostics for hepatitis E virus (HEV) infection are necessary. The aim of our study was to investigate which diagnostic test is most accurate to detect HEV infection in immunocompetent and immunosuppressed ...
Olympia E. Anastasiou, Viktoria Thodou, Annemarie Berger, Heiner Wedemeyer, Sandra Ciesek   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Seroprevalence and risk factors for hepatitis E virus infection in the Romanian adult population: a cross-sectional study in a tertiary hospital

Romanian Journal of Laboratory Medicine, 2019
Background: The primary goal was to estimate the seroprevalence of autochthonous hepatitis E virus (HEV) infection in adult Romanian population. Additionally, we aimed to identify the risk factors associated with the HEV seropositive status.
Gheorghiță Valeriu, Ștefan Ion, Olaru Ioana Diana, Radu Adelina Maria, Săndulescu Oana, Streinu-Cercel Anca, Streinu-Cercel Adrian   +6 more
doaj   +1 more source

Characteristics of the Clinical Course of Autochthonous Hepatitis E in the Central Region of Russia

Журнал инфектологии, 2014
The records of total 123 patients with hepatitis E on treatment in the infectious diseases hospital in the city of Belgorod were reviewed. Diagnosis – «acute hepatitis E» was based on the generally accepted criteria: biochemical analysis, etiological ...
E. Yu. Malinnikova, V. G. Koptyug, M. I. Mikhailov   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Assessment of the efficiency of virus extraction from food matrices and the frequency of occurrence of contaminated products in the retail network

Пищевые системы
Express detection of viruses, in particular, norovirus (NoV) and hepatitis A virus (HAV), is becoming an extremely important task for food safety control.
Yu. K. Yushina, A. A. Semenova, O. A. Kuznecova, D. M. Satabaeva, E. V. Zaiko, B. Velebit   +5 more
doaj   +1 more source

Development of new hepatitis E vaccines

Human Vaccines & Immunotherapeutics, 2018
Hepatitis E virus (HEV) infection is an emerging zoonotic disease posing a severe threat to public health in the world, especially to pregnant women. Currently, no specific treatments are available for HEV infection.
Yufeng Cao, Zhenhong Bing, Shiyu Guan, Zecai Zhang, Xinping Wang   +4 more
doaj   +1 more source

A retrospective clinical and epidemiological analysis of cases of hepatitis E in St. Petersburg

Журнал инфектологии, 2014
Hepatitis E – zoonotic disease that has received a nosological independence twenty years ago, when Russian scientist, Professor M.S. Balayan, identified the pathogen (hepatitis E).
H. D. Peradze, E. V. Esaulenko, E. Y. Malinnikova, M. I. Mihaylov   +3 more
doaj   +1 more source

Hepatitis E virus seroprevalence in indigenous residents of the Hà Giang northern province of Vietnam

Инфекция и иммунитет, 2021
Vietnam is an endemic territory of the South-East Asia in terms of the prevalence of hepatitis E virus. However, the data on the prevalence of HEV infection among the indigenous population of Vietnam are limited, whereas the data on various minor ethnic ...
E. V. Lichnaia, T.H. G. Pham, O. A. Petrova, T. N. Tran, T. T. Nguyen, T.T. N. Bui, V. C. Vo, A. V. Dmitriev, O. V. Kalinina   +8 more
doaj   +1 more source