Results 31 to 40 of about 37,200,073 (264)

Hepatit Hastalarında Serum CTNNβ1 ve E-kadherin Düzeylerinin Değerlendirilmesi

, 2020
Objectives: Hepatitis B virus (HBV) infection is one of the leading causes of hepatocellular carcinoma, but the underlying molecular mechanisms are quite complex.
Çetinkol, Yeliz, Taşpınar, Numan, Cırrık, Selma, Noyan, Tevfik, Şahin, Arzu, Çalgın, Mustafa Kerem, Arzu Şahin, Selma Cırrık, Mustafa Kerem Çalgın, Yeliz Çetinkol, Tevfik Noyan, Numan Taşpınar   +11 more
core   +1 more source

An acute infection due to hepatitis E in the context of a patient with rituximab and methotrexate therapy

European Journal of Case Reports in Internal Medicine
Background: This report presents the influence of immunosuppression by new rheumatological therapies on hepatitis E virus infection in a 54-year-old male patient with an anti-synthetase syndrome and treatment with methotrexate and rituximab.
Francisco Josué Cordero Pérez, Eva P. Martín Garrido, Marta Antona-Herranz, Carmen Bailador-Andrés, Pilar Conde-Gacho, Clara de Diego-Cobos, Santiago J. Rodriguez-Gomez   +6 more
doaj   +1 more source

A Systematic Review of the Extra-Hepatic Manifestations of Hepatitis E Virus Infection

Medical Sciences, 2020
Hepatitis E virus (HEV) is a non-enveloped, positive-sense, single-stranded RNA icosahedral virus belongs to the genus Orthohepevirus within the Hepeviridae family. HEV infection can be asymptomatic, or it can cause icteric or fulminant hepatitis.
Prashanth Rawla, Jeffrey Pradeep Raj, Alan Jose Kannemkuzhiyil, John Sukumar Aluru, Krishna Chaitanya Thandra, Mahesh Gajendran   +5 more
doaj   +1 more source

Severe Hypercholesterolemia Mediated by Lipoprotein X in an Immunosuppressed Patient: A Case Report

GE: Portuguese Journal of Gastroenterology, 2022
Cholestatic liver diseases may be associated with increased plasmatic cholesterol due to an abnormal lipoprotein – lipoprotein X (LpX). Correcting the underlying cause of cholestasis is the critical treatment of LpX-associated hypercholesterolemia ...
Cristiana Sequeira, Mariana Coelho, Inês Costa Santos, Sara Ramos Lopes, João Mangualde, Ana Paula Oliveira   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

High mortality associated with an outbreak of hepatitis E among displaced persons in Darfur, Sudan [PDF]

, 2006
BACKGROUND: Hepatitis E virus (HEV) causes acute onset of jaundice and a high case-fatality ratio in pregnant women. We provide a clinical description of hospitalized case patients and assess the specific impact on pregnant women during a large epidemic ...
Nizou, Jacques-Yves, Klovstad, Hilde, J.-P. Guthmann, Nicand, Elisabeth, Guerin, Philippe Jean, P. J. Guerin, D. Boccia, J.-Y. Nizou, E. Nicand, Tatay, Mercedes, M. Tatay, Ciglenecki, Iza, H. Klovstad, Boccia, Delia, Guthmann, Jean-Paul, I. Ciglenecki, Hamid, Nuha, N. Hamid   +17 more
core   +2 more sources

Community leaders’ experiences of hepatitis E in a Namibian informal settlement: A qualitative study

Journal of Public Health in Africa
Background: The hepatitis E virus (HEV) is a major global health concern, with an estimated one-third of the human population infected. It is particularly prevalent in developing countries, especially in informal settlements where inadequate sanitation ...
Abraham V. Nghikevali, Talitha Crowley
doaj   +1 more source

Molecular epidemiological study of clinical cases of acute hepatitis E in Belarus

Журнал микробиологии, эпидемиологии и иммунобиологии, 2023
Relevance. The frequency of occurrence of anamnestic antibodies to the hepatitis E virus (HEV) in the general population of the Republic of Belarus is 7.3%, which is clearly not consistent with the low incidence of hepatitis E (HE).
Vladimir V. Davydov, Sergey V. Zhavoronok, Tatyana V. Znovets, Vladimir M. Tsyrkunov, Andrei S. Babenkа, Svetlana I. Marchuk, Elena L. Gasich, Tatiana P. Novik, Galina I. Alatortseva, Mikhail I. Mikhailov, Vitaly V. Zverev   +10 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

HEPATITIS E: А NEW PROBLEM IN TRANSPANTOLOGY?

Вестник трансплантологии и искусственных органов, 2012
Hepatitis E is enterically transmitted infection and is the cause of outbreaks and sporadic cases. Disease was originally registered only in the developing subtropical and tropical countries and has been connected with I or II genotypes of hepatitis E ...
M. L. Zubkin, T. A. Semenenko, E. P. Selkova, F. K. Kokoeva, V. I. Chervinko, E. M. Balakirev, V. A. Aleshkin   +6 more
doaj   +1 more source