A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga +66 more
core +1 more source
A Systematic Review of the Extra-Hepatic Manifestations of Hepatitis E Virus Infection
Hepatitis E virus (HEV) is a non-enveloped, positive-sense, single-stranded RNA icosahedral virus belongs to the genus Orthohepevirus within the Hepeviridae family. HEV infection can be asymptomatic, or it can cause icteric or fulminant hepatitis.
Prashanth Rawla +5 more
doaj +1 more source
Estimation of hepatitis E virus transmission among pigs due to contact-exposure
Locally acquired hepatitis E in humans from industrialized countries has been repeatedly suggested to originate from pigs. Pigs may serve as a reservoir of hepatitis E virus (HEV) for humans when a typical infected pig causes on average more than one ...
Saskia A. Rutjes +23 more
core +1 more source
Aim. Determination of prevalence of markers of hepatitis A and E among migrant workers, who had recently arrived in Russian Federation from countries with various degree of endemicity regarding this infection. Materials and methods.
S. D. Alsalikh +4 more
doaj +1 more source
Molecular epidemiological study of clinical cases of acute hepatitis E in Belarus
Relevance. The frequency of occurrence of anamnestic antibodies to the hepatitis E virus (HEV) in the general population of the Republic of Belarus is 7.3%, which is clearly not consistent with the low incidence of hepatitis E (HE).
Vladimir V. Davydov +10 more
doaj +1 more source
Hepatitis E Pathogenesis [PDF]
Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients.
Sébastien Lhomme +5 more
openaire +2 more sources
Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin +5 more
core +1 more source
Experimental Infection of Rabbits with Rabbit and Genotypes 1 and 4 Hepatitis E Viruses
Background: A recent study provided evidence that farmed rabbits in China harbor a novel hepatitis E virus (HEV) genotype. Although the rabbit HEV isolate had 77-79% nucleotide identity to the mammalian HEV genotypes 1 to 4, their genomic organization is
Zheng, L +26 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Transfusion-transmitted hepatitis E
Hepatitis E is an acute and self-limiting viral hepatitis caused by the hepatitis E virus (HEV). It has a higher mortality rate among immunosuppressed patients and pregnant women infected with HEV.
LI Baixun +4 more
doaj +1 more source

