Results 41 to 50 of about 37,200,073 (264)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2016 Hepatitis E (HE) virus infection is not limited to spread from human to human but also occurs between animals and more importantly as zoonotic spread from animals to humans. Genotyping of strains from hepatitis E virus-infected patients has revealed that
Widén, Frederik, +1 more
core +1 more source
Journal of Global Infectious Diseases, 2020 Introduction: The high mortality associated with fulminant Hepatitis E infection in pregnancy justifies the need to assess the epidemiologic proportion of this underestimated virus.
Adeola Fowotade +2 more
doaj +1 more source
Prevalence of antibodies to the hepatitis E virus in the population of the Republic of Belarus
Журнал микробиологии, эпидемиологии и иммунобиологии, 2022 Rationale. Hepatitis E (HE) is a zooanthroponosis. Domestic pigs are the main reservoir for hepatitis E virus (HEV) in the Republic of Belarus (RB). Considering the well-developed pig farming, there is a high risk of infection spread among the population;
V. V. Davydov +9 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Comprehensive Evaluation of Hepatitis E Serology and Molecular Testing in a Large Cohort
Pathogens, 2020 Introduction: Reliable and cost-effective diagnostics for hepatitis E virus (HEV) infection are necessary. The aim of our study was to investigate which diagnostic test is most accurate to detect HEV infection in immunocompetent and immunosuppressed ...
Olympia E. Anastasiou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Living with Hepatitis C: information for people living with Hepatitis C and their families and friends [PDF]
, 2007 Consultative Council on Hepatitis C / [200?
Consultative Council on Hepatitis C
core
Characteristics of the Clinical Course of Autochthonous Hepatitis E in the Central Region of Russia
Журнал инфектологии, 2014 The records of total 123 patients with hepatitis E on treatment in the infectious diseases hospital in the city of Belgorod were reviewed. Diagnosis – «acute hepatitis E» was based on the generally accepted criteria: biochemical analysis, etiological ...
E. Yu. Malinnikova +2 more
doaj +1 more source