The course of hepatitis E virus infection in pigs after contact-infection and intravenous inoculation [PDF]
Background Worldwide, hepatitis E virus (HEV) genotype 3 is observed in pigs and transmission to humans is implied. To be able to estimate public health risks from e.g.
Bouwknegt Martijn +26 more
core +1 more source
Estimation of hepatitis E virus transmission among pigs due to contact-exposure
Locally acquired hepatitis E in humans from industrialized countries has been repeatedly suggested to originate from pigs. Pigs may serve as a reservoir of hepatitis E virus (HEV) for humans when a typical infected pig causes on average more than one ...
Saskia A. Rutjes +23 more
core +1 more source
Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Meng, Xiang-Jin +6 more
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Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick +38 more
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Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad.
The within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced persons living in a Sudanese refugee camp and two camps implanted ...
Guthmann, J P +7 more
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Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Camacho, F. +15 more
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Comorbidities in human immunodeficiency virus infection are of great interest due to their association with unfavorable outcomes and failure of antiretroviral therapy. This study evaluated the prevalence of coinfection by human immunodeficiency virus and
Wornei Silva Miranda Braga +4 more
doaj +1 more source
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy +70 more
core +1 more source
Hepatitis E virus infection in chronic liver disease causes rapid decompensation
Hepatitis E previously known as enterically transmitted non-A, non-B hepatitis, is a self limiting infectious viral disease of developing countries. Various issues regarding the pathogenesis of liver injury and its natural history remain unanswered after
Sudhamshu KC, AK Mishra, R Shrestha
doaj +1 more source
Systematic review of the global epidemiology of viral-induced acute liver failure
Objectives The aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention.Participants This systematic ...
Rudzani Muloiwa +8 more
doaj +1 more source

