Results 41 to 50 of about 32,123,782 (310)

Prevalence and determinants of hepatitis C virus infection among female drug injecting sex workers in Glasgow [PDF]

, 2008
Background: Few studies of the prevalence of hepatitis C virus (HCV) infection have focussed on women who work as street sex workers to finance their drug use. Methods: The investigators report the survey findings of such a population in Glasgow.
Goldberg, David J., Goldberg, DJ, Taylor, Avril, Cameron, Sheila, Carr, Susan, Cameron, S., Susan Carr, Sharon J Hutchinson, Gilchrist, Gail, Hutchinson, S.J., Hutchinson, SJ, Taylor, A, Taylor, A., Gail Gilchrist, Hutchinson, S.J.; id_orcid, Carr, S., Carr, S, Sheila Cameron, Gilchrist, G., Goldberg, David J, Gilchrist, Gail; id_orcid, Goldberg, D.J., Gilchrist, G, Hutchinson, Sharon J., Cameron, S, David J Goldberg, Avril Taylor, Hutchinson, Sharon J   +27 more
core   +4 more sources

Bayesian estimation of hepatitis E virus seroprevalence for populations with different exposure levels to swine in The Netherlands [PDF]

, 2007
Hepatitis E virus (HEV) is ubiquitous in pigs worldwide and may be zoonotic. Previous HEV seroprevalence estimates for groups of people working with swine were higher than for control groups.
W. H. M. VAN DER POEL, M. BOUWKNEGT, van der Poel, W.H.M., Frankena, K., de Jong, M.C.M., Widdowson, M.A., K. FRANKENA, B. ENGEL, M. P. G. KOOPMANS, Poel, W.H.M., van der, A. M. De RODA HUSMAN, Herremans, M.M.P.T., M. A. WIDDOWSON, M. M. P. T. HERREMANS, Worm, H.C., Engel, B., Roda Husman, A.M., de, M. C. M. De JONG, H. C. WORM, Bouwknegt, M., Jong, M.C.M., de, Koopmans, M.P.G., de Roda Husman, A.M.   +22 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Low prevalence of hepatitis B virus, hepatitis D virus and hepatitis C virus among patients with human immunodeficiency virus or acquired immunodeficiency syndrome in the Brazilian Amazon basin Baixa prevalência do vírus da hepatite B, vírus da hepatite D e vírus da hepatite C entre pacientes com o vírus da imunodeficiência humana ou síndrome da imunodeficiência adquirida na Amazônia Brasileira

Revista da Sociedade Brasileira de Medicina Tropical, 2006
Comorbidities in human immunodeficiency virus infection are of great interest due to their association with unfavorable outcomes and failure of antiretroviral therapy. This study evaluated the prevalence of coinfection by human immunodeficiency virus and
Wornei Silva Miranda Braga, Márcia da Costa Castilho, Isabelle Cristina Vale dos Santos, Marco Antônio Sabóia Moura, Aluisio Cotrim Segurado   +4 more
doaj   +1 more source

Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]

, 2012
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Meng, Xiang-Jin, Feagins, Alicia R, Huang, Yao-Wei, Córdoba, Laura, Dryman, Barbara A, Opriessnig, Tanja, Cossaboom, Caitlin M   +6 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Hepatitis E virus infection in chronic liver disease causes rapid decompensation

Journal of Nepal Medical Association, 2006
Hepatitis E previously known as enterically transmitted non-A, non-B hepatitis, is a self limiting infectious viral disease of developing countries. Various issues regarding the pathogenesis of liver injury and its natural history remain unanswered after
Sudhamshu KC, AK Mishra, R Shrestha
doaj   +1 more source

Systematic review of the global epidemiology of viral-induced acute liver failure

BMJ Open, 2020
Objectives The aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention.Participants This systematic ...
Rudzani Muloiwa, Jenna Patterson, Hannah Sophia Hussey, Sheetal Silal, Liz Goddard, Mashiko Setshedi, Wendy Spearman, Gregory D Hussey, Benjamin M Kagina   +8 more
doaj   +1 more source

The Role of Glutathione in Selected Viral Diseases

Antioxidants, 2023
During inflammatory processes, immunocompetent cells are exposed to substantial amounts of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that is an important and ubiquitous antioxidant molecule produced in human ...
Joanna Wróblewska, Marcin Wróblewski, Iga Hołyńska-Iwan, Martyna Modrzejewska, Jarosław Nuszkiewicz, Weronika Wróblewska, Alina Woźniak   +6 more
doaj   +1 more source

Experimental Infection of Rabbits with Rabbit and Genotypes 1 and 4 Hepatitis E Viruses [PDF]

, 2010
Background: A recent study provided evidence that farmed rabbits in China harbor a novel hepatitis E virus (HEV) genotype. Although the rabbit HEV isolate had 77-79% nucleotide identity to the mammalian HEV genotypes 1 to 4, their genomic organization is
Zheng, L, Ma Yuyuan, Zhang, JG, Liu Yunbo, Zhao, CY, Harrison Tim J., Ma Hongxia, Hongxia Ma, Wang, YC, Wang Youchun, Ma, YY, Yuyuan Ma, Sun, SH, Yunbo Liu, Youchun Wang, Ma, HX, Zhao Chenyan, Harrison, TJ, Zheng Lin, Chenyan Zhao, Jingang Zhang, Zhang Jingang, Tim J Harrison, Lin Zheng, Sun Shuhua, Shuhua Sun, Liu, YB   +26 more
core   +2 more sources