Results 41 to 50 of about 296,832 (214)

Outbreak of hepatitis E virus infection in Darfur, Sudan: effectiveness of real-time reverse transcription-PCR analysis of dried blood spots

, 2009
Biological samples collected in refugee camps during an outbreak of hepatitis E were used to compare the accuracy of hepatitis E virus RNA amplification by real-time reverse transcription-PCR (RT-PCR) for sera and dried blood spots (concordance of 90.6%).
Mérens, Audrey, Nicand, E, Mérens, A, Guthmann, JP, Guérin, PJ, Guérin, Philippe Jean, Nicand, Elisabeth, Guthmann, Jean-Paul   +7 more
core   +1 more source

Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions [PDF]

, 2007
Hepatitis C virus (HCV) infection is associated with chronic liver disease and currently affects about 3% of the world population. Although much has been learned about the function of individual viral proteins, the role of the HCV p7 protein in virus ...
Ralf Bartenschlager, Bartenschlager, R., Thomas Pietschmann, Kallis, S., Bartenschlager Ralf, Penin Francois, Penin, F., Patel, A.H., Pietschmann, T., Eike Steinmann, Francois Penin, Steinmann Eike, Steinmann, E., Arvind H Patel, Kallis Stephanie, Patel Arvind H, Stephanie Kallis, Pietschmann Thomas   +17 more
core   +1 more source

Animal Models for Hepatitis E Virus

, 2016
Animal models are one of the most important tools in the study of human hepatitis E virus (HEV) infection. They are particularly important in light of the major limitations of the cell culture system for HEV.
Ling Wang, Wang, Lin, Lin Wang, Wang, Ling   +3 more
core   +1 more source

Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251

Biochemistry and Biophysics Reports, 2018
The chemically synthesized endoperoxide compound N-89 and its derivative N-251 were shown to have potent antimalarial activity. We previously demonstrated that N-89 and N-251 potently inhibited the RNA replication of hepatitis C virus (HCV), which ...
Youki Ueda, Weilin Gu, Hiromichi Dansako, Hye-Sook Kim, Sayaka Yoshizaki, Nobuaki Okumura, Tomohiro Ishikawa, Hironori Nishitsuji, Fumihiro Kato, Takayuki Hishiki, Shinya Satoh, Koji Ishii, Michiaki Masuda, Kunitada Shimotohno, Masanori Ikeda, Nobuyuki Kato   +15 more
doaj   +1 more source

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin, Sanford, Brenton J, Kenney, Scott P, Dryman, Barbara A, Córdoba, Laura, Opriessnig, Tanja   +5 more
core   +1 more source

Genetic Evolution of Hepatitis E Virus

, 2016
Comparative analysis of the genomic sequences of multiple hepatitis E virus (HEV) isolates has revealed extensive genomic diversity among them. Recently, a variety of genetically distinct HEV variants have also been isolated and identified from large ...
Gong, Wanyun, Zeng, Hang, Ling Wang, Wanyun Gong, Yulin Zhang, Hang Zeng, Zhang, Yulin, Wang, Ling   +7 more
core   +1 more source

The Role of Glutathione in Selected Viral Diseases

Antioxidants, 2023
During inflammatory processes, immunocompetent cells are exposed to substantial amounts of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that is an important and ubiquitous antioxidant molecule produced in human ...
Joanna Wróblewska, Marcin Wróblewski, Iga Hołyńska-Iwan, Martyna Modrzejewska, Jarosław Nuszkiewicz, Weronika Wróblewska, Alina Woźniak   +6 more
doaj   +1 more source

Leprosy and hepatitis B coinfection in southern Brazil

Brazilian Journal of Infectious Diseases, 2014
To investigate the association of leprosy with hepatitis B virus (HBV) infection, as yet unknown for South Brazil, we assessed hepatitis B virus coinfection in 199 South Brazilian leprosy patients (119 lepromatous, 15 tuberculoid, 30 borderline, 12 ...
Cleverson Leitão, Denis Ueda, Anna Carolina de Moraes Braga, Angelica B.W. Boldt, Iara J.T. Messias-Reason   +4 more
doaj   +1 more source

Hepatitis E virus is prevalent in the pig population of Lao People's Democratic Republic and evidence exists for homogeneity with Chinese Genotype 4 human isolates

, 2011
The objective of this study was to determine the prevalence and genotypic range of Hepatitis E virus (HEV) in the pig population of northern Lao People's Democratic Republic (PDR).
Jarman, R.G., Khamphouth Vongxay, Thompson, R.C.A., Blacksell, SD, Chinnawirotpisan, P, Vongxay, K., Melanie C. Melendrez, Thompson, RC, Melendrez, MC, Conlan, JV, Stanley Fenwick, Stuart D. Blacksell, Thompson, RCA, James V. Conlan, Conlan, J., Blacksell, S.D., R.C. Andrew Thompson, Chinnawirotpisan, P., Richard G. Jarman, Fenwick, S., Melendrez, M.C., Jarman, RG, Vongxay, K, Fenwick, S, Piyawan Chinnawirotpisan   +24 more
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Hepatitis E virus and fulminant hepatitis–a virus or host‐specific pathology? [PDF]

Liver International, 2014
AbstractBackground & AimsFulminant hepatitis is a rare outcome of infection with hepatitis E virus. Several recent reports suggest that virus variation is an important determinant of disease progression. To critically examine the evidence that virus‐specific factors underlie the development of fulminant hepatitis following hepatitis E virus ...
Smith, Donald B., Simmonds, Peter
openaire   +3 more sources