Results 121 to 130 of about 25,003 (247)

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Short communication
Anti-HCV antibodies detection frequency in groups of patients hospitalized on chosen clinical wards

Archives of Medical Science, 2005
After the outbreak of an endemy of hepatitis C, a number of epidemiological analyses have proven that the HCV infection poses a particular threat to patients and medical personnel.
Magdalena Majek, Łukasz Polański, Mariusz Bełz   +2 more
doaj  

Cholangiocellular hepatocarcinoma

Annals of Hepatology, 2008
Mario Alfonso Reséndiz-Morán, Virgilia Soto-Abraham, Jesús Aguirre-García   +2 more
openaire   +3 more sources

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, Volume 13, Issue 14, 9 March 2026.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

Chromones as Nonclassical Inhibitors of Carbonic Anhydrase IX and XII Isoforms: Probing Chromone‐Based Derivatives

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
Chromone‐based derivatives were synthesized and evaluated for selective inhibition of tumor‐associated carbonic anhydrases IX and XII. Structure–activity relationships, docking studies, and ADMET profiling revealed promising candidates with selective tumoral isoform inhibition, supporting their potential as anticancer leads. ABSTRACT A small library of
Lisa Sequeira, Simona Distinto, Carlos Fernandes, Erica Sanna, Rita Meleddu, Marco Gaspari, Filippo Cottiglia, Alessia Onali, Andrea Angeli, Fernanda Borges, Eugenio Uriarte, Stefano Alcaro, Claudiu T. Supuran, Elias Maccioni   +13 more
wiley   +1 more source

El hepatocarcinoma

Anales del Sistema Sanitario de Navarra, 2016
El hepatocarcinoma (HCC) es la sexta neoplasia más frecuente a nivel mundial, y una de las principales causas de muerte por cáncer. Además, en la mayoría de las ocasiones, asienta sobre una enfermedad hepática previa, y se conocen muchos de los factores de riesgo para desarrollarlo (hepatitis virales, cirrosis alcohólica, esteatohepatitis no alcohólica,
openaire   +4 more sources

Emex spinosa (L.) Campd.: A Review on Ethnomedicinal, Phytochemical, Pharmacological, and Toxicological Profile

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Graphical abstract illustrating the pharmacological potential of E. spinosa. ABSTRACT Emex spinosa (L.) Campd. (E. spinosa) is a plant species belonging to the Polygonaceae family. It is native to the Middle East, North Africa, and Europe and is most commonly seen on the coastlines of Mediterranean countries.
Smail Amtaghri, Kolawole Olofinsan, Mitchel Otieno Okumu, Kopang Clemendi Mokhetho, Shabnoor Iqbal, Innocensia M. Mangoato, Mohamed Amtaghri, Mouloud Lamtai, Mohamed Yassine El Brouzi, Motlalepula G. Matsabisa   +9 more
wiley   +1 more source

Anticancer Peptide fromChinese Toad (Bufo Bufo Gargarizans) Skin Enhanced Sensitivity to 5-Fu in Hepatocarcinoma cells (HepG2)

Cancer Biology & Medicine, 2011
OBJECTIVE To investigate the antiproliferative and apoptogenic activities of peptide extracted from the Chinese toad (Bufo bufogargarizans) skin (TSP) and its effects on hepatocarcinoma cell line.METHODS MTT assaywas used to detect the effects of TSP ...
Chuang-xin LU, Wen-yu WANG, Ning MA, Yao CUI, Xiao-yan LI, Yun ZHOU   +5 more
doaj  

Therapeutic targeting of MALT1 in oncology: Mechanism, inhibitor development, and clinical prospects

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract MALT1, a multifunctional protease molecule, plays a pivotal role in the adaptive immunity by regulating immune cell survival, proliferation and activation through the nuclear transcription factor‐κB (NF‐κB) signaling pathway by scaffold and protease activities.
Xintao Cao, Peixia Wang, Yuan Ji, Yongliang Sun, Dejiu Zhang   +4 more
wiley   +1 more source