Results 131 to 140 of about 21,046 (260)

FBXO10 Drives Hepatocellular Carcinoma Proliferation via K63-Linked Ubiquitination and Stabilization of FRMPD1

open access: yesCurrent Issues in Molecular Biology
Aberrant ubiquitination drives hepatocellular carcinoma (HCC) progression, yet the role of FBXO10—a key F-box E3 ubiquitin ligase component—remains uncharacterized.
Wuguang Liu   +6 more
doaj   +1 more source

Ultrasmall Fe‐curcumin immunomodulators reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence

open access: yesBMEMat, Volume 4, Issue 3, September 2026.
This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan   +15 more
wiley   +1 more source

Resecciones hepáticas en el servicio de Cirugía General del Hospital Privado: 13 años de experiencia resecciones hepáticas.

open access: yesRevista de la Facultad de Ciencias Médicas de Córdoba, 2019
Antecedentes: Las resecciones hepáticas constituyen el tratamiento de elección en las neoplasias hepáticas primarias yen algunos casos de tumores metastáticos, pero conllevan  tasas significativas de morbilidad y mortalidad.
Julia Samamé   +4 more
doaj  

Bioactive Properties of Achillea biserrata M.Bieb. Extracts: Phytochemical Analysis, Antioxidant Activity, Target Enzyme Inhibition, and Cytotoxic Effects

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Integrated evaluation of Achillea biserrata extracts combining LC‐MS/MS phytochemical profiling, antioxidant, enzyme inhibitory, and antiproliferative assays with multivariate chemometric analyses (Pearson correlation, PCA, hierarchical clustering, and PLS regression), revealing phytochemicals associated with the observed biological activities (The ...
Zühal Bayrakçeken Güven   +2 more
wiley   +1 more source

Apresentações incomuns do hepatocarcinoma: ensaio iconográfico

open access: yes, 2017
O objetivo deste trabalho foi descrever e ilustrar aspectos incomuns do hepatocarcinoma na tomografia computadorizada e ressonância magnética. A partir da análise retrospectiva de 100 casos de pacientes com hepatocarcinoma diagnosticado por análise ...
Ribeiro, Marcelo   +8 more
core  

Veratric Acid and the Cytotoxic Activity of Handroanthus impetiginosus Inner Bark Extract: No Association

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Physicochemical characterization, phytochemical profiling, and in vitro cytotoxicity assessment of Handroanthus impetiginosus inner bark extract show that veratric acid, despite being readily identified by HPLC‐DAD, does not account for the observed cytotoxicity.
Gabriela Alberto Gil   +6 more
wiley   +1 more source

Phytochemical Profiling and Biological Evaluation of Pistacia lentiscus L. grown in Chlef (Algeria): An Integrated In Vitro, In Vivo, and In Silico Study

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
The antihypoxic and antioxidant activities of Pistacia lentiscus L. extract are assessed. High total phenolics and flavonoids contents are noted. Various phenolic acids and flavonoids are identified via HPLC‐MS analysis. The extract demonstrates important scavenging and reducing power, enhances mice survival under normobaric hypoxia, and reduces ...
Halima Saiah   +4 more
wiley   +1 more source

Total Phenolic Content, Antioxidant and Cytotoxic Activity of Three Jacaranda Species (Bignoniaceae)

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Jacaranda species (Bignoniaceae) collected in the Serra do Espinhaço—Brazil's only mountain range and home to one of the planet's highest levels of biodiversity—exhibit interesting antioxidant activities and superior selectivity toward the acute monocytic leukemia cell line (THP‐1) when compared to the standard drug cytarabine.
Eliane Cristina Costa   +8 more
wiley   +1 more source

Cinerascensosides A and B, Two New Cytotoxic Sulfated Saponins From the Sea Cucumber Holothuria cinerascens

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Two new saponins cinerascensosides A and B (1 and 2) are isolated from the sea cucumber H. cinerascens. Their structures and absolute configurations are established through extensive spectroscopic analysis, DP4+ probability calculation, and ECD calculations.
Tran Thi Hong Hanh   +5 more
wiley   +1 more source

Dual miRNA‐Mediated Axes Act in Concert in the Antioxidant Action of Eicosapentaenoic Acid: let‐7c‐3p/TFAM Drives Mitochondrial Biogenesis While miR‐34c‐5p/SIRT1 Potentiates Enzymatic Defenses

open access: yesCell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Previous transcriptomic analysis revealed that eicosapentaenoic acid (EPA) alters miRNA expression in HepG2 cells. Two key miRNA‐mRNA axes mediating EPA's antioxidant effects were identified. EPA was found to downregulate let‐7c‐3p, which directly targets mitochondrial transcription factor A (TFAM).
Haiqi Wang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy