Results 121 to 130 of about 15,709 (229)

Structure-Biomedical Activity Relationship of Tunable Ceria-Graphene Nanocomposites Leading to Divergent Cellular Responses. [PDF]

Int J Mol Sci
Magdaș TM, Bâldea I, Bodolea C, Bălan AM, Ștef A, Mǎgeruşan L, Filip GA.   +6 more
europepmc   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source

Retraction: MicroRNA-133b Inhibits Proliferation, Cellular Migration, and Invasion via Targeting LASP1 in Hepatocarcinoma Cells. [PDF]

Oncol Res
Oncology Research Editorial Office.
europepmc   +1 more source

Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang, Chenyang Mu, Rui Zhao, Runwei Ma, Xuehai Liu, Haoling Zhang, Zengwu Wang, Jing‐jing Zhang   +7 more
wiley   +1 more source

Usnic acid induces apoptosis and inhibits cell migration and invasion in hepatocarcinoma cells: in vitro and in silico analysis. [PDF]

BMC Complement Med Ther
Mutlu D.
europepmc   +1 more source

FXR1‐Directed Alternative Splicing of MK5 Drives Hepatocellular Carcinoma Progression by Activating GSK3β Signaling

Cancer Science, Volume 117, Issue 6, Page 1580-1593, June 2026.
The RNA‐binding protein FXR1 promotes hepatocellular carcinoma (HCC) progression by driving alternative splicing of MK5 to generate an oncogenic isoform, MK5‐L, which activates the Wnt/β‐catenin pathway. Targeting FXR1 with an antisense oligonucleotide suppresses tumor growth in vivo, revealing a promising therapeutic strategy for HCC.
Yutong Li, Jin Xiang, Bin Cheng, Chenhao Li, Kai Wang, Ni Tang, Luyi Huang   +6 more
wiley   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, Volume 293, Issue 11, Page 3140-3165, June 2026.
Intra‐tumoral oxygen deprivation (hypoxia) promotes the activation of hypoxia‐inducible factors (HIFs) that orchestrate the transcriptional adaptation of cancer cells to hypoxia. Hypoxia is prevalent in hepatocellular carcinoma (HCC), a cancer type with limited therapeutic options.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

[Clinical and Imaging Features in Patients with Cirrhosis and Hepatocellular Carcinoma at a Tertiary Hospital in Córdoba] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Oliva V, Muiño G, Orozco S, Saad EJ.
europepmc   +1 more source

AFP Stimulates Glucose Metabolic Reprogramming Contributing to Hepatocellular Carcinoma Resist Sorafenib Through Activating PI3K/AKT Signalling Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Alpha fetoprotein (AFP) regulates glucose metabolism reprogramming (GMR) related to drug resistance of hepatocellular carcinoma (HCC) and remains unclear. This study explores the effect of AFP regulating GMR (Glucose metabolic reprogramming) on the tolerance of HCC cells to sorafenib.
Yuli Zhou, Siren Feng, Yi Chen, Bo Lin, Wei Li, Xu Dong, Kun Liu, Qiushi Yin, Mengsen Li, Mingyue Zhu   +9 more
wiley   +1 more source

Technology-Critical Element Exposure Reveals Divergent Toxicity in Different Human Cells Despite Comparable Uptake. [PDF]

Biomolecules
Magdaș TM, Filip GA, Dehelean A, Clichici S, Bodolea C, Bălan AM, Magdaș DA, Crivii CB, Bâldea I.   +8 more
europepmc   +1 more source