Results 41 to 50 of about 33,100 (246)

Hydroxysteroid sulfotransferase SULT2B1b promotes hepatocellular carcinoma cells proliferation in vitro and in vivo. [PDF]

PLoS ONE, 2013
Hydroxysteroid sulfotransferase 2B1b (SULT2B1b) is highly selective for the addition of sulfate groups to 3β-hydroxysteroids. Although previous reports have suggested that SULT2B1b is correlated with cell proliferation of hepatocytes, the relationship ...
Xiaoming Yang, Yali Xu, Fenghua Guo, Yanxia Ning, Xiuling Zhi, Lianhua Yin, Xiaobo Li   +6 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy

Case Reports in Hepatology, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its ...
Oscar Suarez, María Perez, Martin Garzon, Rodrigo Daza, Geovanny Hernandez, Carolina Salinas, Jorge Ceballos, Enrique P. de Leon, Jacqueline Mugnier, Oscar Beltrán, Adriana Varón   +10 more
doaj   +1 more source

Hepatocarcinoma with tumor thrombus occupying the right atrium and portal vein in a patient with hereditary hemochromatosis and liver cirrhosis [PDF]

, 2018
We present the case of a 46-year old patient with Child-Pugh class C cirrhosis with MEDL-Score 16, and hepatocellular carcinoma invading the inferior vena cava and the right atrium.
Breaban, Iulia, Cozma, Angela, Fabian, Ovidiu, Mihailov, Anca, Muresan, Flaviu, Negrean, Vasile, Orasan, Olga Hilda, Sampelean, Dorel, Secara, Sorina Cezara, Stefan, Andreea Maria, Tarmure Sarlea, Simina, Urian, Laura   +11 more
core   +1 more source

Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection [PDF]

, 2017
Tick-borne encephalitis virus (TBEV) is a member of the genus Flavivirus. It can cause serious infections in humans that may result in encephalitis/meningoencephalitis. Although several studies have described the involvement of specific genes in the host
Grubhoffer, Libor, Gu, Quan, Kohl, Alain, Schnettler, Esther, Selinger, Martin, Tong, Lily, Wilkie, Gavin S.   +6 more
core   +2 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Resultados do transplante hepático em portadores de hepatocarcinoma [PDF]

Arquivos de Gastroenterologia, 2001
Racional - O hepatocarcinoma é uma das doenças malignas mais comuns em todo o mundo. O transplante hepático é boa opção terapêutica para os pacientes com hepatocarcinoma em fase inicial, alcançando índices de sobrevida semelhantes aos encontrados nos ...
Mônica Beatriz PAROLIN, Júlio Cézar Uili COELHO, Jorge E. Fouto MATIAS, Vanessa PUCCINELLI, Rossano JARABIZA, Sérgio O. IOSHII   +5 more
doaj   +1 more source

Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis

Pharmaceutics, 2022
A combination of anticancer drugs and chemosensitizing agents has been approached as a promising strategy to potentiate chemotherapy and reduce toxicity in aggressive and chemoresistant cancers, like hepatocellular carcinoma (HCC), cholangiocarcinoma ...
Silvia Di Giacomo, Marco Gullì, Roberta Facchinetti, Marco Minacori, Romina Mancinelli, Ester Percaccio, Caterina Scuderi, Margherita Eufemi, Antonella Di Sotto   +8 more
doaj   +1 more source

Opciones terapéuticas en el carcinoma hepatocelular. Revisión bibliográfica [PDF]

, 2017
El hepatocarcinoma es el principal tumor primario del hígado, representando aproximadamente el 85-90% de las neoplasias primarias hepáticas. Es considerado el 5º cáncer más frecuente en varones, y el 7º en mujeres, apareciendo en torno a las 50-60 ...
Alonso Bartolomé, Santiago, Arias Magadán, Adrián   +1 more
core  

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source