Results 21 to 30 of about 21,046 (260)

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

LA RESONANCIA MAGNÉTICA NUCLEAR DE LA HEPATOCARCINOMA EN LA CIRROSIS HEPÁTICA Y LOS HALLAZGOS DE LA PATOLOGÍA DEL EXPLANTE HEPÁTICO

open access: yesRevista de la Facultad de Medicina Humana, 2017
Objetivos: Determinar la sensibilidad y especificidad de la RMN trifásica con gadolinio en la detección de hepatocarcinoma en pacientes cirróticos que fueron a trasplante hepático y su correlación con los hallazgos del estudio patológico del explante ...
Consuelo Elsa Cornejo-Carrasco
doaj   +1 more source

A Novel Graphene Quantum Dot‐Based mRNA Delivery Platform

open access: yesChemistryOpen, 2021
Abstract: During the last decades, there has been growing interest in using therapeutic messager RNA (mRNA) together with drug delivery systems. Naked, unformulated mRNA is, however, unable to cross the cell membrane and is susceptible to degradation ...
Ya Liu   +6 more
doaj   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

open access: yesHepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol   +22 more
wiley   +1 more source

Comparative Study on the Role of Berberine and Berberis lycium Royle Roots Extract against the Biochemical Markers and Cyclin D1 Expression in HCC Animal Model

open access: yesApplied Sciences, 2021
Diethylamine nitrosamine (DEN), as an initiator of liver tumor, and carbon tetrachloride (CCl4), as a tumor promoter, have been used to study the molecular events of liver cancer in animal models.
Kiren Mustafa   +10 more
doaj   +1 more source

Actualización en el diagnóstico y tratamiento del hepatocarcinoma [PDF]

open access: yes, 2022
Antecedentes: El hepatocarcinoma es una neoplasia maligna de alta prevalencia y constituye una de las principales causas de muerte por este motivo en el planeta.
Ávila Orellana, Pablo Andrés
core   +1 more source

Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis

open access: yesLife, 2021
Primary skin tumors are certainly more frequent than metastatic tumors, but the latter can sometimes be the first sign of otherwise unrecognized neoplastic pathology and always correspond to an advanced stage of the disease.
Gerardo Cazzato   +7 more
doaj   +1 more source

Effect of Allium senescens Extract on Sorafenib Resistance in Hepatocarcinoma Cells

open access: yesApplied Sciences, 2021
Although Allium species are involved in bioactivity, to the best of our knowledge, there is no research on the effects of Allium senescens on drug resistance in hepatocarcinoma.
Sohyeon Park   +4 more
doaj   +1 more source

Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy

open access: yesCase Reports in Hepatology, 2018
Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its ...
Oscar Suarez   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy