Results 11 to 20 of about 15,709 (229)
Deep Learning Algorithms in the Automatic Segmentation of Liver Lesions in Ultrasound Investigations
Life, 2022 Background: The ultrasound is one of the most used medical imaging investigations worldwide. It is non-invasive and effective in assessing liver tumors or other types of parenchymal changes.
Mădălin Mămuleanu +7 more
doaj +1 more source
Revista de la Facultad de Medicina Humana, 2017 Objetivos: Determinar la sensibilidad y especificidad de la RMN trifásica con gadolinio en la detección de hepatocarcinoma en pacientes cirróticos que fueron a trasplante hepático y su correlación con los hallazgos del estudio patológico del explante ...
Consuelo Elsa Cornejo-Carrasco
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A Novel Graphene Quantum Dot‐Based mRNA Delivery Platform
ChemistryOpen, 2021 Abstract: During the last decades, there has been growing interest in using therapeutic messager RNA (mRNA) together with drug delivery systems. Naked, unformulated mRNA is, however, unable to cross the cell membrane and is susceptible to degradation ...
Ya Liu +6 more
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Alternative splicing of IRF3 plays an important role in the development of hepatocarcinoma
Epigenetics, 2023 Alternative splicing is a process causing mRNA translation to produce different proteins, and it is crucial for the development of tumours. In this study, we constructed a prognostic model related to alternative splicing events in hepatocarcinoma using ...
Zhenyi Lv +6 more
doaj +1 more source
Pharmaceutics, 2022 A combination of anticancer drugs and chemosensitizing agents has been approached as a promising strategy to potentiate chemotherapy and reduce toxicity in aggressive and chemoresistant cancers, like hepatocellular carcinoma (HCC), cholangiocarcinoma ...
Silvia Di Giacomo +8 more
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Sodium Valproate Induces Cell Senescence in Human Hepatocarcinoma Cells
Molecules, 2013 Hepatocarcinogenesis is associated with epigenetic changes, including histone deacetylases (HDACs). Epigenetic modulation by HDAC inhibition is a potentially valuable approach for hepatocellular carcinoma treatment.
Hong-Mei An +4 more
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Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Hepatology, EarlyView., 2022 Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source
Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
Case Reports in Hepatology, 2018 Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its ...
Oscar Suarez +10 more
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Hepatology, EarlyView., 2022 The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol +22 more
wiley +1 more source