Results 51 to 60 of about 33,100 (246)

Hepatocarcinoma: estado actual

Galicia Clínica, 2014
El carcinoma hepatocelular (CHC) es la neoplasia primaria hepática más frecuente. Constituye el sexto tumor más habitual en el mundo, con más de 500.000 casos diagnosticados cada año y es la tercera causa más común de muerte por cáncer.Esta enfermedad afecta de manera casi exclusiva a pacientes con hepato-patía crónica que han desarrollado cirrosis ...
Delgado Blanco, Manuel, Pin Vieito, noel, Guerrero Montañés, Alberto   +2 more
openaire   +5 more sources

δ-Aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines [PDF]

, 2002
BACKGROUND: Acute Intermittent Porphyria is a genetic disorder of heme metabolism, characterized by increased levels of porphyrin precursors, delta-aminolevulinic acid (ALA) and porphobilinogen (PBG).
Adriana De Siervi, Elba S Vazquez, Carolina Rezaval, María V Rossetti, Alcira M del Batlle, LA Wetterberg, C AM del Batlle, A De Siervi, JA Stein, HL Bonkowsky, EA Wider de Xifra, F Lithner, L Hardell, R Kauppinen, J Onuki, DP Aden, BB Knowles, GJ Darlington, B Bressac, JK Wilson, P Chomczynski, T Douki, A Batlle, S Helson, R Washbrook, F Wagener, K Nath, V Russel, MC Raff, SW Lowe, L Meijer, M Garrett   +31 more
core   +4 more sources

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Bidirectional interaction of lncRNA AFAP1-AS1 and CRKL accelerates the proliferative and metastatic abilities of hepatocarcinoma cells

Journal of Advanced Research, 2020
Actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1), a long non-coding RNA transcribed from the antisense strand of protein coding gene AFAP1, has attracted attention in cancer research.
Sattar Abdul, Abbasi Majid, Jinxia Wang, Qinlong Liu, Ming-Zhong Sun, Shuqing Liu   +5 more
doaj   +1 more source

Lycopene treatment of prostate cancer cell lines inhibits adhesion and migration properties of the cells [PDF]

, 2014
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
Chopra, Mridula, Cooper, Alan, Elgass, Simone   +2 more
core   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

Frontiers in Oncology, 2019
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in foods such as coffee, wine, tea, and popular medicines such as propolis.
Kaio Murilo Monteiro Espíndola, Roseane Guimarães Ferreira, Luis Eduardo Mosquera Narvaez, Amanda Caroline Rocha Silva Rosario, Agnes Hanna Machado da Silva, Ana Gabrielle Bispo Silva, Ana Paula Oliveira Vieira, Marta Chagas Monteiro   +7 more
doaj   +1 more source

Exacerbation of Anti-Cytomegalovirus Immunity and Mobilization of γ9δ1 T Cells During the Acute Phase of Hepatitis E Virus Infection. [PDF]

Microbiol Immunol
ABSTRACT HEV causes chronic infections that are detrimental to immunocompromised patients. Previous studies showed alterations of γδ T cell subsets at the acute phase of HEV infection. To assess a possible role of CMV, we have examined the frequencies and responses to CMV and HEV of blood γδ T cell subsets from control donors and acute‐phase HEV ...
Retailleau M, Martini F, Abravanel F, Kamar N, Izopet J, Champagne E.   +5 more
europepmc   +2 more sources

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Hepatocarcinoma

Oncología, 2007
El hepatocarcinoma es un tumor con una incidencia creciente y representa la tercera causa de muerte por cáncer a nivel mundial. Presenta variaciones geográficas importantes y está relacionado con múltiples factores ambientales. La intervención sobre estos factores puede modificar su incidencia y su evolución.
Iván Nieto, Freddy Alcarraz, Gregorio Santana   +2 more
openaire   +1 more source