Results 81 to 90 of about 25,003 (247)
BMEMat, EarlyView.This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan +15 more
wiley +1 more source
Molecules, 2017 New 1-[1-(1H-indol-3-yl) alkyl]-1H-indoles, surprisingly, have been obtained from the addition of indole to a variety of aldehydes under neat conditions. CaO, present in excess, was fundamental for carrying out the reaction with paraformaldehyde.
Graziella Tocco +4 more
doaj +1 more source
Cell Death and Disease, 2018 As a calcium-dependent phospholipid binding annexin protein, annexin A5 (Anxa5) links to the progression, metastasis, survival, and prognosis of a variety of cancers.
Xujuan Sun +6 more
semanticscholar +1 more source
Chemistry – A European Journal, EarlyView.5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source
Anales de la Facultad de Medicina, 2018 A nivel mundial, el hepatocarcinoma representa la quinta neoplasia en el sexo masculino y la novena en el sexo femenino. Uruguay no cuenta con estudios epidemiológicos previos, por lo cual el objetivo del presente es analizar la epidemiología del ...
Valentina Berrutti +6 more
doaj
Molecules, 2018 Cancer cells demand high ATP provisions to support proliferation, and targeting of energy metabolism is a good strategy to increase their sensitivity to treatments.
Nathalia F F de Sales +7 more
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito +9 more
wiley +1 more source
The distinct roles of mesenchymal stem cells in the initial and progressive stage of hepatocarcinoma
Cell Death and Disease, 2018 Increasing evidences suggest that mesenchymal stem cells (MSCs) could migrate to the tumor site and play a vital role in tumorigenesis and progression. However, it is still a lively debate whether MSCs exert a pro- or anticancer action.
Chen Zong +10 more
semanticscholar +1 more source
Exploration, EarlyView.The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng +10 more
wiley +1 more source
Cell Adhesion & Migration, 2020 DDR1 is a receptor tyrosine kinases for collagen and an adverse prognostic factor in primary and metastatic tumors.Despite this, DDR1 signaling and its functional consequences in tumor development remain unclear.
Irene Romayor +2 more
doaj +1 more source