Results 171 to 180 of about 2,074,577 (363)

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang, Yunyi Zhang, Xiangyu Meng, Jianli Zhao, Yue Xing, Qian Ouyang, Ning Zhang, Huiping Chen, Nanyan Miao, Erwei Song, Di Huang   +10 more
wiley   +1 more source

Impact of MAFLD on HBV-Related Stage 0/A Hepatocellular Carcinoma after Curative Resection [PDF]

, 2021
Yen‐Po Lin, Shu-Hsien Lin, Chih‐Chi Wang, Chih‐Che Lin, Ding-Wei Chen, Ching‐Hui Chuang, Pao‐Yuan Huang, Chao‐Hung Hung, Shih-Yu Yang, Wei-Ru Cho, Yu-Syuan Chen, Ming‐Chao Tsai   +11 more
openalex   +1 more source

Hepatocellular Carcinoma: a Narrative Review on Current Knowledge and Future Prospects

Current Treatment Options in Oncology, 2023
Basil Alawyia, C. Constantinou
semanticscholar   +1 more source

S···O Conformation Locks Synergistic Alkoxy Chain Engineering of NIR‐II Phototheranostic Molecules for Precision Hepatocellular Carcinoma Theranostics

Advanced Science, EarlyView.
This study introduces a synergistic S‐O conformation locking and alkoxy chain engineering strategy to enhance S‐D‐A‐D‐S molecular planarity. The engineered IR‐BTOG achieves concurrent NIR‐IIa absorption and NIR‐IIb emission, demonstrating exceptional photothermal efficiency and fluorescence quantum yield.
Gui‐long Wu, Fan Wu, Senyou Tan, Hao Xiao, Qiang Kang, Sanlin Deng, Fen liu, Jinkang Zheng, Chaoqiang Li, Guodong Chen, Qinglai Yang   +10 more
wiley   +1 more source

Prediction of potential targets of aloe-emodin in the treatment of hepatocellular carcinoma using network pharmacology combined with bioinformatics

Discover Oncology
Background Hepatocellular carcinoma is one of the most common and malignant tumors worldwide. Although aloe-emodin (AE), a pure natural drug, can effectively kill hepatocellular carcinoma cells, its internal molecular mechanism has not been fully ...
Jinlong Wei, Haosong Chen, Maoqi Xu, Zhenglin Zhang, Jin Wang, Wen Jiang, Weiguo Zhou, Maoming Xiong   +7 more
doaj   +1 more source

The Changes of HIF-1α and VEGF Expression After TACE in Patients With Hepatocellular Carcinoma

, 2016
Kang Liu, Xuli Min, Juan Peng, Ke Yang, Lin Yang, Xiao Ming Zhang   +5 more
openalex   +2 more sources

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

TAF2: A potential oncogene for hepatocellular carcinoma [PDF]

, 2017
Astrocyte Elevated Gene 1 (AEG1) is an oncogene for hepatocellular carcinoma (HCC). Its role in HCC pathogenesis has been well studied. A pan cancer analysis of gene expression in multiple databases identified TATA-box binding protein associated factor 2
Chidambaranathan Reghupaty, Saranya
core   +1 more source

Berbamine (BBM), a Natural STAT3 Inhibitor, Synergistically Enhances the Antigrowth and Proapoptotic Effects of Sorafenib on Hepatocellular Carcinoma Cells [PDF]

, 2020
Weijia Zhao, Binglong Bai, Hong Zhong, Xuming Zhang, Bin Zhou   +4 more
openalex   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source