Results 181 to 190 of about 2,074,577 (363)
Repeat hepatic resection versus percutaneous ablation for the treatment of recurrent hepatocellular carcinoma: meta-analysis [PDF]
, 2022 Bao‐Hong Yuan +5 more
openalex +1 more source
Advanced Science, EarlyView.This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang +8 more
wiley +1 more source
Clinical and Translational MedicineBackground Hepatocellular carcinoma remains one of the most lethal cancers, characterized by poor prognosis and low life expectancy. Unfortunately, there are very few molecular therapeutic options available for it.
Xiaochen Wang +8 more
doaj +1 more source
A cross sectional analysis of the association between FGF19 tumor expression and serum AFP levels in advanced HCC patients [PDF]
, 2017 PURPOSE: HCC is a complicated disease with high mortality rates and limited treatment options. No universal clinical or molecular classification established to inform better treatment options.
Clifford, Corinne
core
Age-specific sex difference in the incidence of hepatocellular carcinoma in the United States
, 2017 Pian Liu +6 more
openalex +2 more sources
An Eastern Hepatobiliary Surgery Hospital Microvascular Invasion Scoring System in Predicting Prognosis of Patients with Hepatocellular Carcinoma and Microvascular Invasion After R0 Liver Resection: A Large-Scale, Multicenter Study [PDF]
, 2019 Xiuping Zhang +14 more
openalex +1 more source
Advanced Science, EarlyView.The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu +16 more
wiley +1 more source
Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma [PDF]
, 2018 Giuseppa Augello +13 more
openalex +1 more source
Advanced Science, EarlyView.METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang +18 more
wiley +1 more source