Results 211 to 220 of about 2,029,665 (367)

Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma

Acta Pharmaceutica Sinica B, 2021
Danyu Du, Chan Liu, Mengyao Qin, Xiao Zhang, Tao Xi, S. Yuan, Haiping Hao, Jing Xiong   +7 more
semanticscholar   +1 more source

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

Advanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra, Justin Garland, Rajani Rai, Donghua Zhao, Charuksha Walgama, Sadagopan Krishnan, Andrew T. Long, Tongzu Liu, Laura Adhikari, Doris M. Benbrook   +9 more
wiley   +1 more source

Hepatocellular Carcinoma: A Comprehensive Review. [PDF]

Diseases
Amin N, Anwar J, Sulaiman A, Naumova NN, Anwar N.   +4 more
europepmc   +1 more source

Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice

Advanced Science, EarlyView.
Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu, Kaiqiang Li, Huasong Liu, Aibo Xu, Zhewei Zhang, Yimin Yang, Xiaobo Lai, Ke Hao, Kui Fang, Zeyu Lai, Xiping Ou, Yuqun Cai, Zhen Wang, Keda Lu, Wanli Jiang   +14 more
wiley   +1 more source

Splenectomy and risk of hepatocellular carcinoma. [PDF]

World J Hepatol
Li DQ, Lin ZY, Wang JG, Wu RQ, Zhang Y, Du ZQ.   +5 more
europepmc   +1 more source

Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria.

, 1976
Arthur I. Cederbaum, Frederick F. Becker, Emanuel Rubin   +2 more
openalex   +1 more source

Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma

Seminars in liver disease (Print), 2010
Riccardo Lencioni1, Josep Llovet2 , 3
semanticscholar   +1 more source

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

A Patient Charter to Improve Care for Hepatocellular Carcinoma. [PDF]

J Hepatocell Carcinoma
Hassan Y, Kautz A, James C, Lee D, Langenbacher D, Bouffet E, Chakowa J, Hicks J, Ward JW, Kuschnereit LA, Allaire M, Zhang T, Huang Chi Z.   +12 more
europepmc   +1 more source

Study on association of Hepatocellular Carcinoma with Hepatitis B Virus Infection: Bangladesh Perspective

, 1970
Babul Osman Chowdhury, Mustaque Ahamad, AHM Omer Farooque, A.K.M Shahidur Rahman   +3 more
openalex   +2 more sources