Results 231 to 240 of about 690,479 (320)

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma. [PDF]

Biomedicines
Li C, Lu B, Deng B.
europepmc   +1 more source

Cranial Metastasis of Hepatocellular Carcinoma

, 1985
Satoshi Nakao, Shinichi Sato, T Fukumitsu, M Ogata, Hirofumi Shirane   +4 more
openalex   +2 more sources

Molecular cloning of an oncogene from a human hepatocellular carcinoma. [PDF]

, 1986
Takahiro Ochiya, Asao Fujiyama, S. Fukushige, I. Hatada, Kouki Matsubara   +4 more
openalex   +1 more source

GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation

Advanced Science, EarlyView.
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim, Quan Pan, Zeyu Liu, Weiqi Ai, Hye Won Han, Sakhila K. Banu, Robert Y.L. Tsai, Gus A. Wright, Shaodong Guo, Yuxiang Sun   +9 more
wiley   +1 more source

Targeting inflammatory pathways in hepatocellular carcinoma: recent developments. [PDF]

Discov Oncol
Ramaite FT, Nkadimeng SM.
europepmc   +1 more source

Experimental studies on hepatocarcinogenesis by oral contraceptives, synthetic estrogen and progestogen, with special reference to the hormone dependency of the developed hepatocellular carcinoma.

, 1986
S. Uehara
openalex   +2 more sources

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

Basal metabolic rate shapes the development and progression of hepatocellular carcinoma. [PDF]

BMC Cancer
Maciak S, Sawicka D, Kasacka I, Chyczewski L, Car H, Konarzewski M.   +5 more
europepmc   +1 more source

Lymphokine-activated killer activity and natural killer activity in patients with hepatocellular carcinoma.

, 1987
Hiroshi SAKAEDA, Toshiji Saibara, Saburo Onishi   +2 more
openalex   +2 more sources