Results 231 to 240 of about 2,074,577 (363)
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang +9 more
wiley +1 more source
Hepatocellular carcinoma: Epidemiology, diagnosis and treatment. [PDF]
Mauro E +6 more
europepmc +1 more source
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang +15 more
wiley +1 more source
A bibliometric analysis of atezolizumab in hepatocellular carcinoma. [PDF]
Xu Y, Zhang H, Yu H.
europepmc +1 more source
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
PANoptosis in hepatocellular carcinoma: Underlying mechanisms. [PDF]
Li MJ, Wen CL, Cheng HT, Lyu HN, Han YY.
europepmc +1 more source

