Results 241 to 250 of about 2,074,577 (363)

Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma

Seminars in liver disease (Print), 2010
Riccardo Lencioni1, Josep Llovet2 , 3
semanticscholar   +1 more source

Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification.

Advances in Cancer Research, 2021
Saranya Chidambaranathan-Reghupaty, P. Fisher, D. Sarkar   +2 more
semanticscholar   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Sleep disorders in hepatocellular carcinoma. [PDF]

World J Gastrointest Oncol
Qian J, Ruan MH, Wang ZJ, Dong W, Jia JY, Feng XC, Liu H.   +6 more
europepmc   +1 more source

Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma

Acta Pharmaceutica Sinica B, 2021
Danyu Du, Chan Liu, Mengyao Qin, Xiao Zhang, Tao Xi, S. Yuan, Haiping Hao, Jing Xiong   +7 more
semanticscholar   +1 more source

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

Therapeutic Potential of Nanoscale Metal-Organic Frameworks in Hepatocellular Carcinoma. [PDF]

Nanomaterials (Basel)
Tutunchi H, Nabipour H, Rohani S.
europepmc   +1 more source

Metabolic alterations and mitochondrial dysfunction underlie hepatocellular carcinoma cell death induced by a glycogen metabolic inhibitor

, 2022
Shrikant Barot, Olivia J. Stephenson, Hari Priya Vemana, Anjali Yadav, Shraddha Bhutkar, Louis D. Trombetta, Vikas V. Dukhande   +6 more
openalex   +1 more source

Deep Learning‐Powered Nanoplasmonic Biosensing Approach Enables Ultrasensitive Extracellular Vesicles Profiling for Cancer Screening

Advanced Science, EarlyView.
This study presents a Kolmogorov–Arnold network (KAN)‐powered nanoplasmonic biosensing platform for ultrasensitive detection of small extracellular vesicles in serum, enabling highly accurate pancreatic cancer screening. The method achieves an area under the curve (AUC) of 0.99 in a large clinical cohort, offering a robust and interpretable deep ...
Jiaheng Zhu, Yingqi Xiao, Xinyue Huang, Qiang Niu, Lihuang Zeng, Shaowei Lin, Mengqi Jiang, Tianhao Huang, Hanyang Chen, Yinong Xie, Yuan Gao, Wei Chen, Yiming Yan, Jiaqing Shen, Kaibin Chen, Yurong Dai, Zhipeng Zhang, Lijun Zeng, Yahong Chen, Boan Li, Jinfeng Zhu, Bo Li   +21 more
wiley   +1 more source

Mechanisms of ferroptosis in primary hepatocellular carcinoma and progress of artificial intelligence-based predictive modeling in hepatocellular carcinoma. [PDF]

World J Gastroenterol
Han JF, Jia ZY, Fan X, Zhao XY, Cheng LY, Xia YX, Ji XR, Zang WQ.   +7 more
europepmc   +1 more source