Results 251 to 260 of about 715,584 (321)

Myocarditis induced by durvalumab in a patient with hepatocellular carcinoma: A case report. [PDF]

Saudi Pharm J
Alfehaid L, Alsuhebany N, Aldoughaim M, Bukhari R, Sait W, Alshammari K, Aziz M.   +6 more
europepmc   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

MEX3A: A promising prognostic marker and therapeutic target in hepatocellular carcinoma. [PDF]

World J Gastrointest Oncol
Yang XL, Yang XJ.
europepmc   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo, Kunzhao Huang, Xiaoyuan Yi, Pei Lu, Huaying Xie, Wen Li, Qingyu Zeng, Feifei He, Duo Wang, Liyan Wang   +9 more
wiley   +1 more source

Sorafenib with or without co-interventions for hepatocellular carcinoma. [PDF]

Cochrane Database Syst Rev
Chen S, Liu JP, Li X, Dang S, Li W.
europepmc   +1 more source

A case of lupoid hepatitis associated with hepatocellular carcinoma.

, 1987
Seiya Arima, Ken Yoshida, Osamu Hashiguchi, Shun‐ichi Kimura, Seiichi Ooishi, Shigetoshi Fujiyama, Katsuro Sagara, Tatsuo Sato   +7 more
openalex   +2 more sources

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

Advanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang, Hongyuan Zhu, Zeen Zhu, Shuai Wu, Yiqun Song, Jin Wang, Xinlong Chen, Weikun Qian, Jianpeng Li, Yangyang Yue, Qinhong Xu, Zhiping Ruan, Qing Li, Yaomin Zhu, Tian Jian Lu, Guy M. Genin, Feng Xu, Zheng Wang, Min Lin   +18 more
wiley   +1 more source

KBTBD11 suppresses hepatocellular carcinoma by targeting ENO1-mediated glycolysis. [PDF]

J Transl Med
Liu Y, Chen Y, Tang L, Lin F, Zhuang Q, Chen H, Lin X, Li J.   +7 more
europepmc   +1 more source

Hepatocellular carcinoma in ground squirrels persistently infected with ground squirrel hepatitis virus.

, 1986
Patricia L. Marion, Mary Jo Van Davelaar, S S Knight, Felix H. Salazar, Gabriella Garcia, Hans Pópper, William H. Robinson   +6 more
openalex   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source