Results 271 to 280 of about 2,029,665 (367)

A Nano‐Electro‐Platform Enabling Evolutionary Screening and Remodeling of Tumor Cells for Metastasis Inhibition

Advanced Science, EarlyView.
The nano‐electro‐platform achieves non‐destructive evolutionary screening and electro‐remodeling of tumor cells to generate extracellular vesicles with enhanced tumor‐targeting and therapeutic functions. These extracellular vesicles demonstrate remarkable efficacy in activating both macrophages and T cells, thereby orchestrating a potent immune ...
Feng Liu, Hong Sun, Bing Liu, Jing Zhang, Chengbao Wu, Shi Yan, Chengzheng Tai, Yihang Tong, Rongtai Su, Xiaowei Xiang, Han Wu, Fuqi Yao, Kuan Yang, Dedong Yin, Yuqiong Wang, Ao Xiao, Long Cheng, Xi Chen, Nan Wu, Zaizai Dong, Lingqian Chang   +20 more
wiley   +1 more source

Anti-Angiogenic Agents for Advanced Hepatocellular Carcinoma Induce Liver Atrophy. [PDF]

Cancer Med
Wake T, Yamada T, Tateishi R, Moriyama M, Matsushita Y, Okushin K, Nakatsuka T, Sato M, Minami T, Kudo Y, Fujishiro M.   +10 more
europepmc   +1 more source

Experimental studies on hepatocarcinogenesis by oral contraceptives, synthetic estrogen and progestogen, with special reference to the hormone dependency of the developed hepatocellular carcinoma.

, 1986
S. Uehara
openalex   +2 more sources

Targeting Seipin to Alleviate Hepatic Steatosis in Zebrafish (Danio Rerio)

Advanced Science, EarlyView.
Seipin plays a crucial role in lipid metabolism. Seipin overexpression ameliorates high‐fat‐diet‐induced hepatic steatosis and enhances growth in zebrafish. Mechanistically, Seipin interacts with Plin2 to promote Plin2 degradation and enhances phosphatidylcholine synthesis via Seipin/CCTα/CHPT interactions.
Weijia Li, Yanan Shen, Zengqi Zhao, Baolin Li, Shunlang Wen, Rui Zhan, Qinghui Ai   +6 more
wiley   +1 more source

Potential role of gut bacteria in the development of hepatocellular carcinoma. [PDF]

Access Microbiol
Yan B, Wang Y, Wang Z, Huang A, Jin X, Jiang T, Xue H, Shen Z, Wang S, Xu H, Zhu R.   +10 more
europepmc   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

The changing face of hepatic resection [PDF]

, 1989
Iwatsuki, S, Sheahan, DG, Starzl, TE
core   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

The role of GALAD score in the surveillance of hepatocellular carcinoma. [PDF]

Sci Rep
İstemihan Z, Şenkal İV, Karaca D, Nuriyev K, Rustamzade A, Genç Uluçeçen S, Dağcı G, Yağlı MA, Gurbanov A, Telli P, Çavuş B, Çifcibaşı Örmeci A, Akyüz F, Demir K, Beşışık F, Kaymakoğlu S.   +15 more
europepmc   +1 more source

Personalized Neoantigen Vaccine plus Regorafenib Increases Rgs2⁺CD8⁺ T Cells Infiltration and Reprograms the Tumor Microenvironment in Microsatellite Stable Colorectal Cancer Liver Metastases

Advanced Science, EarlyView.
This study synthesized a personalized neoantigen vaccine (Neo‐CRCVAS) and combined it with regorafenib, termed RegoNeo. This combination therapy significantly enhanced antitumor efficacy and promoted long‐term tumor‐specific immune memory in microsatellite stable colorectal cancer liver metastasis (MSS‐CRLM) models by increasing neoantigen‐specific ...
Hengkai Chen, Bin Chen, Yuanfeng Yang, Shoufeng Li, Huajun Cai, Zhicheng Zhuang, Yong Wu, Yuan Gao, Yupeng Chen, Xing Liu, Guoxian Guan, Jinfu Zhuang   +11 more
wiley   +1 more source