Results 21 to 30 of about 690,479 (320)

Elevated N‐methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform

Molecular Oncology, 2019
The cross‐talk between hepatic stellate cells (HSCs) and hepatic carcinoma cells contributes to hepatocellular carcinoma (HCC) progression, but the underlying mechanism is largely unknown.
Jie Li, Song You, Sheng Zhang, Qing Hu, Fuqiang Wang, Xiaoqin Chi, Wenxiu Zhao, Chengrong Xie, Changmao Zhang, Yaqi Yu, Jianmin Liu, Yue Zhao, Pingguo Liu, Yi Zhang, Xujin Wei, Qiu Li, Xiaomin Wang, Zhenyu Yin   +17 more
doaj   +1 more source

The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. [PDF]

, 2011
Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable delivery of the unique drug combinations needed for personalized medicine.
Ashley, Carlee E, Brinker, C Jeffrey, Brown, Page A, Carnes, Eric C, Carroll, Nick J, Carter, Mark B, Chackerian, Bryce, Dunphy, Darren R, Durfee, Paul N, Evans, Deborah G, Hanna, Tracey N, Jiang, Xingmao, Liu, Juewen, Padilla, David, Parikh, Atul N, Peabody, David S, Petsev, Dimiter N, Phillips, Brandy, Phillips, Genevieve K, Wharton, Walker, Willman, Cheryl L   +20 more
core   +2 more sources

A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]

, 2015
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W, Faltermeier, Claire, Zarrinpar, Ali   +2 more
core   +2 more sources

Basic and Clinical Research Progress of Immunotherapy for Hepatocellular Carcinoma

Zhongliu Fangzhi Yanjiu, 2023
Primary liver cancer, especially hepatocellular carcinoma, poses a serious threat to the life and health of the Chinese people. Given the insidious onset of liver cancer, less than 30% of hepatocellular carcinoma patients are considered for radical ...
ZHANG Zechuan, SUN Beicheng
doaj   +1 more source

Hepatocellular carcinoma and multidrug resistance: Past, present and new challenges for therapy improvement [PDF]

, 2015
Hepatocellular carcinoma (HCC) is the most common malignancy of the liver and the third cause of cancer death worldwide. Chronic hepatitis due to HBV and HCV infection are two major risk factors for HCC worldwide.
Cuestas, María Luján, Mathet, Veronica Lidia, Oubiña, Jose Raul   +2 more
core   +1 more source

hsa_circ_0006916 promotes hepatocellular carcinoma progression by activating the miR-337-3p/STAT3 axis

Cellular & Molecular Biology Letters, 2020
Background Circular RNAs (circRNAs) are thought to be involved in the development of various malignancies. The expression and function of hsa_circ_0006916, a newly identified circRNA, in hepatocellular carcinoma remain unclear.
Xiao-Yong Zhou, Hui Yang, Yang-Qiu Bai, Xiu-Ling Li, Shuang-Yin Han, Bing-Xi Zhou   +5 more
doaj   +1 more source

Development and Validation of a New Prognostic System for Patients with Hepatocellular Carcinoma [PDF]

, 2016
BACKGROUND: Prognostic assessment in patients with hepatocellular carcinoma (HCC) remains controversial. Using the Italian Liver Cancer (ITA.LI.CA) database as a training set, we sought to develop and validate a new prognostic system for patients with ...
Benvegnu', Luisa, Biasini, Elisabetta, Borzio, Franco, Cabibbo, Giuseppe, Caturelli, Eugenio, Ciccarese, Francesca, Cillo, Umberto, Di Marco, Mariella, Farinati, Fabio, Felder, Martina, Foschi, Francesco Giuseppe, Frigo, Anna Chiara, Gasbarrini, Antonio, Giacomin, Anna, Giannini, Edoardo G., Huo, Teh La, Lee, Yun Hsuan, Masotto, Alberto, Morisco, Filomena, Pawlik, Timothy M., Piscaglia, Fabio, Rapaccini, Gian Lodovico, Sacco, Rodolfo, Spolverato, Gaya, Svegliati Baroni, Gianluca, Trevisani, Franco, Virdone, Roberto, Vitale, Alessandro, Zoli, Marco   +28 more
core   +4 more sources

CDK5-mediated phosphorylation and stabilization of TPX2 promotes hepatocellular tumorigenesis

Journal of Experimental & Clinical Cancer Research, 2019
Background CDK5, an atypical member of the CDK family, play a significant role in the tumorigenesis of multiple organ, but CDK5 and its substrates in genesis and development of HCC is still unclear.
Fuqiang Wang, Wenxing Zhao, Yuehong Gao, Jiechao Zhou, Huifang Li, Guanyun Zhang, Dong Guo, Chengrong Xie, Jie Li, Zhenyu Yin, Jie Zhang   +10 more
doaj   +1 more source

Spatially resolved visualization of reprogrammed metabolism in hepatocellular carcinoma by mass spectrometry imaging

Cancer Cell International, 2023
Background Metabolic reprogramming refers to tumor-associated metabolic alterations during tumorigenesis and has been regarded as one of the most important features of cancer.
Bangzhen Ma, Yang Zhang, Jiwei Ma, Xinguo Chen, Chenglong Sun, Chengkun Qin   +5 more
doaj   +1 more source

miR-100 Suppresses the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells via Targeting CXCR7

Journal of Immunology Research, 2021
This study is to elucidate the functions of miR-100 in hepatocellular carcinoma progression and to explore the underlying mechanisms. Expression levels of miR-100 in normal-cancer hepatocellular carcinoma tissues were measured using quantitative real ...
Yiman Ge, Jia Shu, Gang Shi, Fuguo Yan, Yejing Li, Hangliang Ding   +5 more
doaj   +1 more source