Results 71 to 80 of about 941,442 (284)

Protein profiling in hepatocellular carcinoma by label-free quantitative proteomics in two west african populations. [PDF]

open access: yes, 2013
21.08.13 KB.
Maimuna E Mendy   +75 more
core   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Stabilization of FASN by USP5-mediated deubiquitination promotes hepatocellular carcinoma progression

open access: yesOncogenesis
The deubiquitinating enzyme Ubiquitin specific peptidase 5 (USP5) has attracted substantial notice for its vital role in cancer progression. However, the USP5-mediated deubiquitination of corresponding protein substrates and its functional role in ...
Qinliang Fang   +9 more
doaj   +1 more source

Network pharmacology integrated with molecular docking and experimental validation elucidates the therapeutic potential of Forsythiae Fructus extract against hepatitis B virus-related hepatocellular carcinoma

open access: yesFrontiers in Oncology
BackgroundForsythiae Fructus (FF), a widely used traditional Chinese medicine, possesses anti-inflammatory, antiviral, and anticancer properties. However, the precise anticancer mechanisms of FF against hepatitis B virus (HBV)-related hepatocellular ...
Fuqing Chen   +3 more
doaj   +1 more source

The overexpression of Rabl3 is associated with pathogenesis and clinicopathologic variables in hepatocellular carcinoma

open access: yesTumor Biology, 2017
Overexpression of Rabl3 is associated with some malignancies. However, their relationship with hepatocellular carcinoma remains unclear. In this study, the expression of Rabl3 in hepatocellular carcinoma cell lines, and four pairs of matched ...
Yuhang Pan   +6 more
doaj   +1 more source

Effect of interferon-alpha on progression of cirrhosis to hepatocellular carcinoma: a retrospective cohort study.

open access: yes, 1998
BACKGROUND: There is debate about whether interferon-alpha treatment lowers the risk of progression to hepatocellular carcinoma in patients with chronic viral hepatitis and cirrhosis and whether any effect is limited to certain subgroups. We investigated
(INTERNATIONAL HEPATOCELLULAR CARCINOMA STUDY GROUP   +3 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Role of mTOR system and its relation with somatostatin and dopamine receptors on cell proliferation, hormone secretion and intracellular signalling in hepatocellular and cholangiocellular carcinomas. [PDF]

open access: yes, 2011
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are among the most lethal of human malignancies with s a very poor prognosis, with a
Pivonello, Claudia
core   +1 more source

Regulation of adenovirus replication by miR-199 confers a selective oncolytic activity in hepatocellular carcinoma [PDF]

open access: yes, 2012
Oncolytic virotherapy represents a growing field of experimental cancer therapy. For safe and effective virotherapy, restricted tissue expression and replication of the virus is desirable.
Khalid Elamin Elhag, Baha Eldin
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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