Results 171 to 180 of about 140,561 (343)

Serum Tumor Necrosis Factor-alpha Concentration and its Prognostic Implication in Hepatocellular Carcinoma

open access: yesBiomolecular and Health Science Journal
Introduction: Hepatocellular carcinoma (HCC) progression is closely to inflammatory pathways, with tumor necrosis factor-alpha (TNF-α) recognized as a central mediator.
Vembi Rizky Fatmawati   +3 more
doaj   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

open access: yesExploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng   +10 more
wiley   +1 more source

Protective effect of L-arginine against necrosis and apoptosis induced by experimental ischemic and reperfusion in rat liver

open access: yesThe Saudi Journal of Gastroenterology, 2009
Background/Aim: To study the effect of L-arginine on apoptosis and necrosis induced by 1-h ischemia followed by 3-h reperfusion. Materials and Methods: Adult Wistar rats underwent 60 min of partial liver ischemia followed by 3-h reperfusion.
Chattopadhyay Pronobesh   +2 more
doaj  

A case of hepatic segmental atrophy mimicking spontaneously necrotized hepatocellular carcinoma

open access: yesRadiology Case Reports
We report a rare case of hepatic segmental atrophy that was initially suspected to be hepatocellular carcinoma (HCC). An 80-year-old man presented with a new 3 cm hepatic lesion that met LI-RADS-5 criteria.
Hitomi Kamiya, MD   +7 more
doaj   +1 more source

Focal hepatocellular necrosis following varicella a similarity with endotoxin-induced focal hepatocellular necrosis

open access: yesFocal hepatocellular necrosis following varicella a similarity with endotoxin-induced focal hepatocellular necrosis
We report a case of ulcerative colitis with random and focal hepatocellular coagulative necrosis caused by varicella following administration of adrenocortical steroids and immunosuppressive agents. At autopsy, damage of the sinusoidal endothelial cells due to infection with varicella-zoster viruses and formation of fibrin thrombi in the sinusoids were
openaire  

Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1 [PDF]

open access: gold, 2013
Xuelei Cao   +11 more
openalex   +1 more source

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