Results 271 to 280 of about 140,561 (343)

Transcatheter arterial chemoembolisation of hepatocellular carcinoma in transplant patients: smaller bead diameter and hypervascularity lead to higher tumour necrosis

, 2013
Michael Hakky
openalex   +1 more source

Fatal Dengue Fever in a Traveler Returning from Togo to Germany. [PDF]

Am J Trop Med Hyg
Kohsar M, Haar M, Schmidt-Chanasit J, Ramharter M, Buchholz BM, Krasemann S, Bernreuther C, Cadar D, Omansen TF, Wichmann D, Ko LM, Jordan S.   +11 more
europepmc   +1 more source

Biomimetic MCC950‐loaded cerium‐layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin‐induced mice

British Journal of Pharmacology, EarlyView.
The CLMBM nanoparticle (NP) system demonstrates strong and targeted anti‐ROS, antiapoptotic and anti‐inflammatory properties within the pancreas, thereby inhibiting the onset and progression of type 1 diabetes. Background and Purpose The destruction of β‐cells in type 1 diabetes is driven by signalling cascades that ultimately lead to cell apoptosis ...
Huiwen Pang, Zhuo Chen, Youzhi Wu, Thanh‐Truc Nguyen, Jingjing Wang, David M. Klyne, Zhi Ping Xu, Chen Chen, Alan Rowan, Felicity Y. Han   +9 more
wiley   +1 more source

TNFAIP1 suppresses hepatocellular carcinoma progression via the PXR/CYP3A4 signaling axis. [PDF]

Am J Cancer Res
Nie Q, Guo Y, Xiao H, Zhang D, Li H, Wang L.   +5 more
europepmc   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, EarlyView.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

The two cases of massive spontaneous necrosis of hepatocellular carcinoma after angiography

, 2010
Keita Kai, Atushi Miyoshi, Keisuke Ario, Kenji Kitahara, Toshihiko Mizuta, Seiji Kawazoe, Hiroyuki Irié, Osamu Tokunaga, Hirokazu Noshirο, Kohji Miyazaki   +9 more
openalex   +2 more sources

Context-dependent contribution of peptidyl arginine deiminase 4 (PAD4) to neutrophil extracellular trap formation and liver injury in acute and chronic hepatotoxicant challenge. [PDF]

Toxicol Sci
Capece GE, Patel AK, Hu D, Roychowdhury T, Hazel B, Kothapalli J, Mac NA, Denorme F, Campbell RA, Poole LG.   +9 more
europepmc   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Cadmium implication in massive hepatocellular necrosis and hepatic amyloidosis and the protective role of ivermectin and Allium cepa in adult Wistar rats (Rattus Novergicus)

Dare J. Babatunde, Babawale O. Damilola, Alabi P. Adegoke, Adebowale Adebiyi, Obembe Olaleye Olawale, Ebele Cinderela, John Olabode Fatoki   +6 more
openalex   +2 more sources

ABT-737 efficiently inhibits hepatocellular carcinoma cell activity via regulating PANoptosis. [PDF]

Discov Oncol
Deng B, Jin X, Ye D, Liu H, Qin Y, Chen X.   +5 more
europepmc   +1 more source