Results 21 to 30 of about 288,978 (228)

Social Support, Self-Management Behaviors, and Coping Styles of Patients With Wilson's Disease: A Quantitative Empirical Research. [PDF]

Brain Behav
ABSTRACT Purpose Based on Roy's Adaptation Model, this study explores the relationship between social support, coping styles, and self‐management behaviors in patients with Wilson's disease (WD), as well as the underlying mechanisms. Methods A cross‐sectional survey was conducted among 230 WD patients from a tertiary hospital using the Social Support ...
Zhan T, Li X, Wang Y, Wang L, Sun C, Hu X, Qiao S, Li X, Tu W.   +8 more
europepmc   +2 more sources

Gandou Decoction Decreases Copper Levels and Alleviates Hepatic Injury in Copper-Laden Hepatolenticular Degeneration Model Rats. [PDF]

Front Pharmacol, 2020
Objective: This study was designed to investigate the therapeutic efficacy and underlying mechanisms of Gandou Decoction (GDD) in copper-laden hepatolenticular degeneration (HLD) model rats. Methods: In this study, high-performance liquid chromatography (
Wang N, Cheng M, Zhang X, Wu H, Wu H, Cao S, Wu P, Zhou A.   +7 more
europepmc   +2 more sources

A Diagnosis Hidden in Plain Sight: A Rare Presentation of Isolated Dysarthria in Wilson's Disease-A Case Report. [PDF]

Clin Case Rep
ABSTRACT A clinical picture of isolated dysarthria is relatively uncommon, and the underlying condition causing it can be easily misdiagnosed. In this case, a 24‐year‐old Indian male presented with complaints of slurring of speech occurring for the past 9 months. The patient also complained of difficulty swallowing food using his tongue. There was also
Reddy K, Singhvi M, Netto AB, Thejus B, Souza LD, Shivananda DB, Nair SV, Rai D.   +7 more
europepmc   +2 more sources

Identification of miRNAs Expression Characteristics and Biomarkers in Serum-Derived Exosomes of Wilson's Disease Patients. [PDF]

Mediators Inflamm
Background Wilson’s disease (WD), caused by mutations in the ATP7B gene, leads to copper accumulation and multi‐organ damage. Exosomal microRNAs (miRNAs) play a crucial role in cell‐to‐cell communication and the pathogenesis of diseases, yet their study in WD remains unreported.
Chen H, Wang X, Ma Y, Pu Y, Ye H, Zhang J.   +5 more
europepmc   +2 more sources

Doença de Wilson no sul do Brasil: correlação genotípica-fenotípica\ud e a descrição de duas novas mutações no gene ATP7B [PDF]

, 2013
OBJECTIVE:\ud \ud Wilson's disease (WD) is an inborn error of metabolism caused by abnormalities of the copper-transporting protein encoding gene ATP7B.
Araújo, Thiago Ferreira de, Barbosa, Egberto Reis, Bem, Ricardo Schmitt de, Cançado, Eduardo Luiz Rachid, Deguti, Marta Mitiko, Munhoz, Renato Puppi, Muzzillo, Dominique Araújo, Nakhle, Maria Cristina, Raskin, Salmo, Teive, Hélio Afonso Ghizoni   +9 more
core   +4 more sources

Classification and Clinical Heterogeneity of Hepatolenticular Degeneration

Personalized Psychiatry and Neurology, 2023
Hepatolenticular degeneration (HLD) or Wilson-Konovalov disease (OMIM277900) is a hereditary monogenic autosomal recessive degenerative disease related to metabolic diseases - a category of storage diseases.
E. V. Ovchinnikova, E. Vaiman, N. A. Shnayder, A. A. Ovchinnikova, R. Nasyrova   +4 more
semanticscholar   +1 more source

Wilson’s disease in pregnancy: case series and review of literature [PDF]

, 2013
Background: Wilson’s disease is a rare, autosomal recessive inherited disorder characterized by impaired liver metabolism of copper leading to decreased biliary excretion and incorporation of ceruloplasmin levels mainly in the liver and brain.
Khawaja, Ali, Malik, Ayesha, Sheikh, Lumaan   +2 more
core   +4 more sources

Dysarthria in Wilson's disease: analysis of two cases in different stages [PDF]

, 2010
BACKGROUND: dysarthria in Wilson's disease. PROCEDURES: case study of two patients with disease's diagnosis, both young female adults, with six years of schooling. Perceptual analysis was done by four speech therapists.
Barreto, Simone Dos Santos, Brabo, Natália Casagrande, Cera, Maysa Luchesi, Ortiz, Karin Zazo   +3 more
core   +1 more source

Diagnosis and treatment of hepatolenticular degeneration

Медицинский совет, 2013
Hepatolenticular degeneration (Wilson-Konovalov disease or hepatolenticular disease) is a rare hereditary disease caused by impaired copper metabolism and copper accumulation in the liver and, subsequently, in other organs.
V. V. Skvortsov, O. A. Leshina
doaj   +1 more source

Tratamento Endovascular da Disseção Crónica Isolada da Aorta Abdominal [PDF]

, 2016
Isolated acute abdominal aortic dissection is a relatively rare event. Its natural history is not fully understood and its optimal treatment is not established.
Almeida, R., Loureiro, L., Machado, R., Rego, D.   +3 more
core   +1 more source