Results 121 to 130 of about 229,729 (307)

Translational Gap in Biomarker Discovery: Tumor Surface Markers Rarely Mirror Circulating Levels

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Tumor‐associated cell surface proteins are frequently proposed as circulating biomarkers for colorectal cancer (CRC) based on their high tumor expression. However, many candidates identified through tissue‐based analyses fail to translate into clinically useful biomarkers.
Junko Mukohyama, Shohei F. Fujita, Xinyi Fu, Shigenori Suzuki, Hiroki Hamamoto, Dai Shida, Kimihiro Yamashita, Kohei Taniguchi, Sang‐Woong Lee, Akihide Yoshimi   +9 more
wiley   +1 more source

Preconsultation Exchange for Ambulatory Hepatology Consultations [PDF]

, 2013
BACKGROUND: Preconsultation exchange is an emerging model of specialty care proposed by the American College of Physicians that seeks to answer a clinical question without a formal patient visit to the specialty clinic.
Sewell, Justin L, Guy, Jennifer, Yee, Hal F, Kwon, Annette, Chen, Alice Hm   +4 more
core   +1 more source

Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice

Journal of Lipid Research
Metabolic dysfunction-associated steatotic liver disease is the most common form of liver disease and poses significant health risks to patients who progress to metabolic dysfunction-associated steatohepatitis.
Tomasz K. Bednarski, Mohsin Rahim, Clinton M. Hasenour, Deveena R. Banerjee, Irina A. Trenary, David H. Wasserman, Jamey D. Young   +6 more
doaj   +1 more source

Multifocal hepatic steatosis mimicking malignancy in two siblings

JGH Open, 2019
Multifocal hepatic steatosis (MHS) is a rare subtype of hepatic steatosis which can pose a diagnostic challenge due to difficulty in distinguishing it from malignant disease.
John Freebody, Giulio Comin, Eva Segelov, Lisa Tarlinton   +3 more
doaj   +1 more source

Single‐Incision Laparoscopy‐First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes

Annals of Gastroenterological Surgery, EarlyView.
In this retrospective study of 289 patients with Crohn's disease undergoing a single‐incision laparoscopy‐first (SILS‐first) strategy, conversion to open surgery was required in only 11.8% of cases. Fistula formation, colon resection, and smoking history were identified as independent risk factors for conversion, while postoperative complications and ...
Yuki Horio, Motoi Uchino, Yusuke Tomoo, Kentaro Nagano, Kurando Kusunoki, Ryuichi Kuwahara, Kei Kimura, Kozo Kataoka, Masataka Ikeda, Hiroki Ikeuchi   +9 more
wiley   +1 more source

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis [PDF]

, 2006
Background/Aims: The expression of transporters involved in bile acid homeostasis is differentially regulated during obstructive cholestasis. Since the drug efflux transporter breast cancer resistance protein (BCRP) is known to transport bile acids, we ...
Beuers, Ulrich, Lehmann, Frank, Terracciano, Luigi, Hruz, Petr, Zimmermann, Christian, Gutmann, Heike, Drewe, Juergen, Beglinger, Christoph   +7 more
core   +1 more source

On achieving gender equity within the liver transplantation medical and surgical workforce

Frontiers in Transplantation
Until relatively recently there has been a paucity of readily available information pertaining to the demographics of the medical and surgical workforces for the subspecialty of liver transplantation.
Deborah Verran
doaj   +1 more source

Prevention in Hepatology

Journal of Personalized Medicine
The prevention of liver disease has improved significantly in the last few decades, to the point that it can now be considered a true success story. The wide variety of interventions, including comprehensive vaccination strategies, novel medications, lifestyle changes, and even preventive surgeries, have reduced the morbidity and mortality of chronic ...
Ana-Maria Muñoz-Restrepo, Maria-Cristina Navas, Jimmy Daza, Marcos Girala, Ezequiel Ridruejo, Guido Gerken, Andreas Teufel   +6 more
openaire   +3 more sources

Trends, Demographic Characteristics and Seasonal Patterns of Rectal Prolapse Surgery in Japan: A Nationwide Claims‐Based Analysis From 2014 to 2023

Annals of Gastroenterological Surgery, EarlyView.
This study analyzed nationwide trends, demographic characteristics, and seasonal patterns of rectal prolapse surgery in Japan using healthcare claims data. From 2014 to 2023, age‐adjusted overall and conventional surgeries declined significantly, whereas laparoscopic surgeries increased significantly.
Masamitsu Kido, Tomohiro Arita, Hiroki Shimizu, Jun Kiuchi, Kenji Nanishi, Katsutoshi Shoda, Hiroyuki Okimura, Atsuko Fujihara, Kengo Yoshii, Atsushi Shiozaki   +9 more
wiley   +1 more source

Ensuring the Future Pool of Gastroenterologists in the United Kingdom Is Imperative

JGH Open
This perspective article explores the importance of fostering interest in gastroenterology among medical students and addressing the barriers that deter them from pursuing careers in this specialty.
Hareesha Rishab Bharadwaj, Medha Sridhar Rao, Aditya Gaur, Khabab Abbasher Hussien Mohamed Ahmed, Arkadeep Dhali   +4 more
doaj   +1 more source