Results 121 to 130 of about 242,511 (240)

Clinical utility of pharyngeal high‐resolution manometry with impedance for upper esophageal sphincter dysfunction in gastroenterology

Advances in Digestive Medicine, EarlyView.
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar, Taher Omari, Michal Szczesniak, Chien‐Lin Chen, Richard Heddle, Charles Cock   +5 more
wiley   +1 more source

Various Hepatic Fibrosis Markers Should Be Evaluated for Causing Complications After Hepatectomy

Annals of Gastroenterological Surgery, EarlyView.
Toru Ikegami, Hiroshi Nakanishi, Kanako Maeda, Kenei Furukawa   +3 more
wiley   +1 more source

AI Powered Biobanks From Static Archives to Dynamic Discovery Engines

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) provide a potential framework for transforming biobanks from static data repositories into intelligent discovery engines. By enabling unified representation and analysis of multimodal biomedical data, LLM‐based systems facilitate dynamic risk prediction, biomarker identification, and mechanistic interpretation, thereby ...
Wenzhen Yin, Yutian Feng, Wenrui Ma, Yuxin Su, Li Min, Juan Liu   +5 more
wiley   +1 more source

A multicenter multistate modeling on the natural history of liver decompensation: Longitudinal analysis of 1777 patients. [PDF]

Hepatol Commun
Tan EXX, Tang NSY, Syn N, Huang DQ, Kulkarni AV, Zheng MH, Chen VL, Rattananukrom C, Lai JC, Wijarnpreecha K, Kumar R, Kaewdech A, Ueno M, Roy A, Liu K, Nakamura T, Gao Y, Yoneda M, Seko Y, Kimura T, Nourredin M, Siddiqui MS, Takahashi H, Ng CH, Muthiah M, CORE Consortium.   +25 more
europepmc   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

The Childhood Liver Disease Research Network's prospective characterization of pediatric primary sclerosing cholangitis. [PDF]

Hepatol Commun
Mack CL, Miethke AG, Hawthorne K, Henn L, Horslen S, Alonso EM, Gupta NA, Sundaram SS, Kohli R, Bozic M, Deneau M, Guthery S, Loomes KM, Valentino PL, Tessier MEM, Shneider B, Magee JC, Karpen S, Rosenthal P, Wang K, Ricciuto A, Sokol RJ, Kamath BM, Childhood Liver Disease Research Network (ChilLDReN).   +23 more
europepmc   +1 more source

Temperature‐Controlled Radiofrequency for Severe Nasal Airway Obstruction: A Non‐Inferiority Comparison With Surgical Intervention

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Temperature‐controlled radiofrequency (TCRF), septoplasty (ST) with turbinate reduction, and functional rhinoplasty (FR) are treatment options for nasal airway obstruction (NAO) and nasal valve dysfunction (NVD), but no direct comparison of these procedures has been performed. Methods This prospective, open‐label, non‐inferiority (
Greg Davis, Zeeshan Aziz, Jose Barrera, William Blythe, Chris Davis, Steven Davis, Thomas Higgins, Charles Lano, Gregory Levitin, Frederick Lopatin, Samuel Oyer, Stacey Silvers, Ariel Waitzman, Randall Ow   +13 more
wiley   +1 more source

Evolving patient journey in the management of active perianal fistulizing Crohn's disease: A temporal perspective. [PDF]

Colorectal Dis
Bak MTJ, Verweij MM, Stassen LPS, Buskens CJ, Pronk AM, van der Bilt JDW, Munster LJ, de Boer NKH, Gecse KB, Pierik RB, Witjes CDM, Fitzpatrick CE, Breukink SO, Pierik MJ, Nissen LHC, Verdaasdonk EGG, Gilissen LPL, Bloemen JG, Mares WGN, de Jong GM, Sikkema M, Zimmerman DDE, Bierens-Peters D, de Jonge V, Smeenk RM, Jharap BJ, de Witte E, Romberg-Camps M, Bodelier AGL, Ayez N, Vos XG, van Herwaarden MA, Bos-Poliste S, Indemans FA, van Boeckel PGA, Voskuil MD, van der Wouden EJ, van Dalsen AD, Willemsen-Maas S, Vandebosch S, van Dessel E, Adang RPR, Konsten JLM, van Aalten SM, Wobbes MH, van der Zanden EP, Veltkamp SC, Pultrum BB, Ter Steege RWF, Tielemans MM, van der Have M, Zuur AT, Ter Borg PCJ, Braat H, Aukema TS, Stuyt RJL, van Rossem CC, Verweij KE, van Oostendorp JY, Han-Geurts I, van Tongeren P, Govaert JA, van der Marel S, Horjus CS, Jansen JM, Jansen SV, Bloemendaal ALA, West RL, Kortekaas RTJ, Peeters KCMJ, van der Meulen-de Jong AE, van Schaik FDM, Richir MC, van Dongen KW, Duijvestein M, Bouwknegt DG, Hoogenboom FJ, Visschedijk MC, de Vries AC, van Ruler O, Dutch Initiative on Crohn and Colitis (ICC) & Dutch Initiative on Crohn and Colitis‐Surgery (ICC‐S).   +80 more
europepmc   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source