Results 81 to 90 of about 297,520 (322)

Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation

JCI Insight, 2022
Hepatocellular carcinoma (HCC) is a leading cause of death among cirrhotic patients, for which chemopreventive strategies are lacking. Recently, we developed a simple human cell-based system modeling a clinical prognostic liver signature (PLS) predicting
Emilie Crouchet, Shen Li, Mozhdeh Sojoodi, Simonetta Bandiera, Naoto Fujiwara, Hussein El Saghire, Shijia Zhu, Tongqi Qian, Fahmida Akter Rasha, Fabio Del Zompo, Stephen C. Barrett, Eugénie Schaeffer, Marine A. Oudot, Clara Ponsolles, Sarah C. Durand, Sarani Ghoshal, Gunisha Arora, Fabio Giannone, Raymond T. Chung, Nevena Slovic, Nicolaas Van Renne, Emanuele Felli, Patrick Pessaux, Joachim Lupberger, Nathalie Pochet, Catherine Schuster, Kenneth K. Tanabe, Yujin Hoshida, Bryan C. Fuchs, Thomas F. Baumert   +29 more
doaj   +1 more source

CT and MRI imaging and interpretation of hepatic arterioportal shunts [PDF]

, 2019
Hepatic arterioportal shunts (HAPS) occur due to organic or functional fistulization of blood flow between arterial hepatic vasculature and venous portal systems.
Akisik, Fatih, Cui, Enming, Deng, Yu, Hu, Maoqing, Koniaris, Leonidas G., Milgrom, Daniel P., Patel, Aash, Wang, Qiushi   +7 more
core   +1 more source

Prognostic significance of six autoantibodies in esophageal squamous cell carcinoma: A prospective multi‐institutional study

Annals of Gastroenterological Surgery, EarlyView.
The six autoantibodies (Sui1, p62, RalA, p53, NY‐ESO‐1 and c‐myc) positive group had poor prognosis compared to autoantibody negative group. A panel of autoantibodies against a tumor associated antigen in esophageal cancer patients had an additive effect with SCC‐Ag to detect esophageal SCC even in early stage.
Fumiaki Shiratori, Naoto Fujiwara, Yasuaki Nakajima, Koji Otsuka, Masahiko Murakami, Satoru Matsuda, Hirofumi Kawakubo, Keita Takahashi, Yuichiro Tanishima, Daiji Oka, Shunichi Ito, Kosuke Narumiya, Osamu Aramaki, Tadatoshi Takayama, Takashi Suzuki, Satoshi Yajima, Hideaki Shimada   +16 more
wiley   +1 more source

Insulin resistance associates with hepatic lobular inflammation in subjects with obesity [PDF]

, 2019
Purpose: Obese subjects with nonalcoholic fatty liver disease (NAFLD) are more prone to develop additional metabolic disturbances such as systemic insulin resistance (IR) and type 2 diabetes.
Batens, Arsène-Hélène, Bekaert, Marlies, Geerts, Anja, Hoorens, Anne, Lapauw, Bruno, Ouwens, Margriet, Shadid, Samiah, Van de Velde, Frederique, Van Nieuwenhove, Yves   +8 more
core   +1 more source

The impact of delayed adjuvant chemotherapy on survival in gastric cancer patients with and without preoperative chemotherapy

Annals of Gastroenterological Surgery, EarlyView.
Delayed initiation of adjuvant chemotherapy (AC) is associated with significantly poorer postoperative survival in patients with gastric cancer, irrespective of whether preoperative chemotherapy was administered. These findings emphasize the importance of timely AC initiation to improve long‐term outcomes in this patient population.
Masataka Shimonosono, Takaaki Arigami, Daisuke Matsushita, Yusuke Tsuruda, Ken Sasaki, Kenji Baba, Takao Ohtsuka   +6 more
wiley   +1 more source

Corrigendum: Stem Cell Therapy in Dengue Virus-Infected BALB/C Mice Improves Hepatic Injury

Frontiers in Cell and Developmental Biology, 2022
S. Sakinah, Sivan Padma Priya, Pooi Ling Mok, Pooi Ling Mok, Rusheni Munisvaradass, Seoh Wei Teh, Zhong Sun, Badr Alzahrani, Faizal Abu Bakar, Hui-Yee Chee, Rukman Awang Hamat, Guozhong He, Chenglong Xiong, Narcisse Joseph, Jia Bei Tong, Xiaoyun Wu, Mahendran Maniam, Antony V. Samrot, Akon Higuchi, Akon Higuchi, S. Suresh Kumar, S. Suresh Kumar   +21 more
doaj   +1 more source

Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2

JCI Insight, 2022
Senescent cells have long been associated with deleterious effects in aging-related pathologies, although recent studies have uncovered their beneficial roles in certain contexts, such as wound healing.
Naiyuan Cheng, Ki-Hyun Kim, Lester F. Lau   +2 more
doaj   +1 more source

Osteopenic occult vertebral fracture is associated with poor oncological outcome in patients with hepatocellular carcinoma after hepatic resection

Annals of Gastroenterological Surgery, EarlyView.
Osteopenic occult vertebral fracture (OVF) was associated with poor long‐term outcomes in patients with HCC after hepatic resection. Osteopenic OVF had a poorer prognosis than that of patients with either osteopenia or OVF. Abstract Background Although osteopenia has been associated with poor outcomes in patients with hepatocellular carcinoma (HCC ...
Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Masashi Tsunematsu, Michinori Matsumoto, Tomohiko Taniai, Yoshihiro Shirai, Shinji Onda, Ryoga Hamura, Toru Ikegami   +9 more
wiley   +1 more source

Keeping the Path towards Even Brighter Times

GE: Portuguese Journal of Gastroenterology, 2021
Diogo Libânio, Carolina Palmela, Luís Maia, Miguel Areia   +3 more
doaj   +1 more source

Advantages of subtotal gastrectomy for upper third gastric cancer: A systematic review and meta‐analysis

Annals of Gastroenterological Surgery, EarlyView.
We revealed that subtotal gastrectomy (STG) has its advantage over total gastrectomy on shorter operation time, less complication rates, and lower body weight loss by meta‐analysis. Although there are some controversies, STG can be an ideal option for patients with gastric cancer of upper third stomach.
Yuichiro Miki, Tsubasa Bito, Yasufumi Koterazawa, Shingo Kanaji, Hisashi Shinohara   +4 more
wiley   +1 more source