Results 1 to 10 of about 84,796 (234)

Clinical and ultrasonographic investigations of 30 water buffaloes (Bubalus bubalis) with hepatomegaly [PDF]

Veterinary World, 2019
Background and Aim: Knowledge of normal ultrasonographic dimensions of the liver and associated vascular structures is an important indicator for the diagnosis of hepatic diseases.
A. M. Abdelaal, M. Abd El Raouf, M. A. Aref, A. A. Moselhy   +3 more
doaj   +2 more sources

Formimidoyltransferase cyclodeaminase prevents the starvation-induced liver hepatomegaly and dysfunction through downregulating mTORC1

PLoS Genetics, 2021
The liver is a crucial center in the regulation of energy homeostasis under starvation. Although downregulation of mammalian target of rapamycin complex 1 (mTORC1) has been reported to play pivotal roles in the starvation responses, the underpinning ...
Wenfeng Zhang Zhang, Qifen Yang, Rui Ni
exaly   +2 more sources

Hepatomegaly Associated with Non-Obstructive Sinusoidal Dilation in Experimental Visceral Leishmaniasis

Pathogens, 2021
Visceral leishmaniasis (VL) is the most severe form of leishmaniasis caused by protozoan parasites of the genus Leishmania. Hepatomegaly is one of the most frequent clinical manifestations of VL, whereas immunopathology of the symptom has not been well ...
Kota Maeda, Sonya Sadoughi, Ayako Morimoto, Kazuyuki Uchida, James K. Chambers, Chizu Sanjoba, Junya Yamagishi, Yasuyuki Goto   +7 more
doaj   +2 more sources

In vivo Efficacy and Safety Evaluation of Lactosyl-β-cyclodextrin as a Therapeutic Agent for Hepatomegaly in Niemann-Pick Type C Disease

Nanomaterials, 2019
Niemann-Pick type C disease (NPC) is a fatal, autosomal recessive disorder, which causes excessive accumulation of free cholesterol in endolysosomes, resulting in progressive hepatomegaly and neurodegeneration.
Keiichi Motoyama, Taishi Higashi, Toru Takeo   +2 more
exaly   +2 more sources

Glycogenic hepatopathy – An underrecognised cause of transaminitis in primary care settings: A case report [PDF]

Malaysian Family Physician
Glycogenic hepatopathy (GH) is a rare but reversible hepatic condition associated with poorly controlled type 1 diabetes mellitus (T1DM). It results from excessive glycogen accumulation in hepatocytes, leading to hepatomegaly and elevated liver enzyme ...
Nordiyana Zainul Abidin, Ying Ying Ng, Rosnani Zakaria, Noor Aellmas Samsuddin   +3 more
doaj   +2 more sources

Aflatoxin Exposure May Contribute to Chronic Hepatomegaly in Kenyan School Children

Environmental Health Perspectives, 2012
Background: Presentation with a firm type of chronic hepatomegaly of multifactorial etiology is common among school-age children in sub-Saharan Africa. Objective: Aflatoxin is a liver toxin and carcinogen contaminating staple maize food. In this study we
Yun Yun Gong, Michael N Routledge
exaly   +2 more sources

Mauriac syndrome: a rare complication in patients with type 1 diabetes mellitus [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Mauriac syndrome is a rare complication in patients with type 1 diabetes. It presents with poor glycemic control and hepatomegaly due to extensive liver glycogen deposition.
João Oliveira Torres, Diana Cruz Martins, Alexandra Abegão Matias, Nuno Gião, Eduardo Dutra, Rui Malheiro, Milena Mendes, José Silva-Nunes   +7 more
doaj   +2 more sources

PXR mediates mifepristone-induced hepatomegaly in mice

Acta Pharmacologica Sinica, 2021
Fei Li, Hui-Chang Bi
exaly   +2 more sources

NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly

Journal of Hepatology, 2020
Feng He, , Shinichiro Yamachika
exaly   +2 more sources

Hepatomegaly [PDF]

Pediatric Care Online, 2020
Key Points Hepatomegaly results from increase in the number or size of cells in the liver. Liver span correlates more strongly with hepatomegaly than projection below the costal margin. As a sign, not itself a disease, hepatomegaly can result from broad categories of disorders with an extensive differential diagnosis.
K. Gupta, P. Carmichael, A. Zumla
  +5 more sources