Results 131 to 140 of about 49,728 (243)

Herpes Simplex Virus Hepatitis: An Overlooked Cause of Acute Liver Failure Across a Broad Spectrum of Immunocompromise

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Herpes simplex virus (HSV) infection is common worldwide, but hepatic involvement is rare. HSV hepatitis is an uncommon yet frequently catastrophic cause of acute hepatitis and acute liver failure (ALF), accounting for < 1% of ALF cases while carrying very high mortality when diagnosis and antiviral therapy are delayed ...
Mario U. Mondelli   +5 more
wiley   +1 more source

Cytochrome P450 1a (CYP1A)‐Knockout Javanese Medaka Fish Exhibit Diabetic Traits and Reduced Reproductive Capacity

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Analyses of cytochrome P450 1a (CYP1A)‐knockout (KO) Javanese medaka (Oryzias javanicus) revealed that CYP1A is involved in glucose regulation and reproduction. In the KO fish, significant increases in hepatic transcripts of insulin, glucagon, and somatostatin genes, as well as elevated blood glucose, liver mass, and liver triglyceride levels ...
Suhaila Rusni   +10 more
wiley   +1 more source

Hepatomegaly and Splenomegaly: An Approach to the Diagnosis of Lysosomal Storage Diseases

open access: yes
Clinical findings of hepatomegaly and splenomegaly, the abnormal enlargement of the liver and spleen, respectively, should prompt a broad differential diagnosis that includes metabolic, congestive, neoplastic, infectious, toxic, and inflammatory ...
Hoi Yee Wu   +7 more
core   +1 more source

Hepatic Amyloid Light-Chain Amyloidosis Incidentally Diagnosed via Endoscopic Ultrasound-Guided Liver Biopsy. [PDF]

open access: yesACG Case Rep J
Tsujiguchi Y   +7 more
europepmc   +1 more source

PPARα/γ ragaglitazer eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly

open access: yes, 2003
Peroxisome proliferator-activated receptor (PPAR)α and PPARγ agonists lower lipid accumulation in muscle and liver by different mechanisms. We investigated whether benefits could be achieved on insulin sensitivity and lipid metabolism by the dual PPARα/γ
Ellis, B (15562130)   +10 more
core  

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