Niemann-Pick type C (NPC) disease is a multisystem disorder resulting from mutations in the NPC1 gene that encodes a protein involved in intracellular cholesterol trafficking. Significant liver dysfunction is frequently seen in patients with this disease.
Eduardo P. Beltroy +3 more
doaj +1 more source
Physiological Response Of Laying Birds To Neem (Azadirachta Indica) Leaf Meal-Based Diets: Body Weight Organ Characteristics And Haematology [PDF]
A 12-weeks feeding trial was conducted to evaluate the effects of Neem (Azadirachta indica) leafmeal (NLM) on body weight gain, carcass and organ characteristics and haematological values of laying hens.
Esonu B, O +5 more
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Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature
This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi +13 more
wiley +1 more source
A Rare Side Effect of Entecavir: Hepatomegaly and Steatosis
Hepatomegaly and steatosis are rare but potentially fatal side-effects of nucleoside analogues. Here, we present the case of development of hepatomegaly and steatosis in a 53-year-old male who had been treated with entecavir for five years. There were no
Tayibe BAL +2 more
doaj +1 more source
Automated CT and MRI Liver Segmentation and Biometry Using a Generalized Convolutional Neural Network. [PDF]
PurposeTo assess feasibility of training a convolutional neural network (CNN) to automate liver segmentation across different imaging modalities and techniques used in clinical practice and apply this to enable automation of liver biometry.MethodsWe ...
Bahrami, Naeim +14 more
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Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis. [PDF]
Palmitic acid (PA) induces hepatocyte apoptosis and fuels de novo ceramide synthesis in the endoplasmic reticulum (ER). Myristic acid (MA), a free fatty acid highly abundant in copra/palmist oils, is a predictor of nonalcoholic steatohepatitis (NASH) and
Alarcón-Vila, C +9 more
core +2 more sources
A Comparative Study of Ultrasonography and CT Venography in the Diagnosis of Budd‐Chiari Syndrome
Budd‐Chiari syndrome (BCS) is characterized by hepatic venous outflow obstruction from the hepatic veins to the junction of the inferior vena cava (IVC) and right atrium. Ultrasound (US) and CT venography (CTV) are used as imaging techniques for the diagnosis of BCS, and We compared the diagnostic efficacy of the two modalities. The results showed that
Tiling Jiang +6 more
wiley +1 more source
Major diagnosis for mediastinal and abdominal lymphadenopathy is lymphoma and tuberculosis. Spontaneous remarkable evolution should discuss viral infection on the condition that no corticosteroids have been taken before as they could magically improve an
Fares Ben Salem +4 more
doaj +1 more source
Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario +4 more
core +4 more sources
Abstract Objectives Shwachman‐Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its hepatic phenotype is poorly defined. Our objective was to systematically characterize the prevalence, features, and outcomes of liver injury in a multicenter SDS cohort. Methods Retrospective registry study of 171 patients with biallelic Shwachman‐
Jane Koo +16 more
wiley +1 more source

