Results 81 to 90 of about 37,879 (224)

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Global developmental delay with psychotic disorder at onset of late-infantile form of Niemann-Pick disease type C: A case report

Alʹmanah Kliničeskoj Mediciny
Niemann-Pick disease type C (NP-C) is a rare, progressive, autosomal recessive neurodegenerative disorder with onset at various ages, caused by pathogenic variants in the NPC1 or NPC2 genes.
Dmitriy V. I, Tatiana N. Proskokova
doaj   +1 more source

Treatment Patterns, Outcomes and Survival Trends in T‐Cell Prolymphocytic Leukemia: A Nationwide Population‐Based Study in the Netherlands

European Journal of Haematology, EarlyView.
ABSTRACT Background T‐cell prolymphocytic leukemia (T‐PLL) is a rare, aggressive mature T‐cell malignancy with limited therapeutic options. Alemtuzumab remains the backbone of therapy, and fit responders are consolidated with allogeneic stem cell transplantation (alloSCT). However, contemporary population‐level outcomes remain poorly defined.
Mirian Brink, Arie C. van der Spek, Jeanette K. Doorduijn, Koen de Heer, Sabina Kersting, Lidwine W. Tick, Doreen G. te Raa, Hanneke M. van der Straaten, Gerrit Jan Veldhuis, Laurens Laterveer, Rogier Mous, Mark‐David Levin, Kees Meijer, Andre Mulder, M. Nijland, Gerwin Huls, Arnon P. Kater, Mar Bellido   +17 more
wiley   +1 more source

A young male with non-resolving consolidation and hepatosplenomegaly

Non-resolving consolidation refers to the persistence of radiographic abnormalities beyond the anticipated timeframe. Conditions such as infection, malignancy, inflammatory disorders, and connective tissue diseases can all manifest as non-resolving ...
Gaurav Khanna, Sourabh Pahuja, Arjun Khanna, Pradeep Bajad, Satyam Agarwal   +4 more
core   +1 more source

Prognostic Value of Skin Lesion Characteristics in Subcutaneous Panniculitis‐Like T‐Cell Lymphoma: A Retrospective Cohort Study Assessing the Applicability of T Category of the TNM Classification for Primary Cutaneous Lymphomas Other Than Mycosis Fungoides and Sézary Syndrome

International Journal of Dermatology, EarlyView.
Subcutaneous panniculitis‐like T‐cell lymphoma. Survival outcomes according to the presence of hemophagocytic lymphohistiocytosis (HLH) and T category. Relapse‐free survival was inferior in patients presenting with generalized (T3) skin lesions. Overall survival was poor in patients with HLH. Relapse‐free survival was also reduced in patients with HLH.
Myoung Eun Choi, Joon Min Jung, Soo Hyun Jeon, Chong Hyun Won, Sung Eun Chang, Mi Woo Lee, Woo Jin Lee   +6 more
wiley   +1 more source

ICSH Guidance on Bone Marrow Examination and Reporting

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology   +6 more
wiley   +1 more source

Precursor‐targeted immune‐mediated anaemia in a dog with concurrent haemoparasite seroreactivity: Diagnostic challenges and therapeutic response

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary Precursor‐targeted immune‐mediated anaemia (PIMA) is an increasingly recognised cause of nonregenerative anaemia in dogs and may be difficult to distinguish from infectious or other immune‐mediated conditions. This report describes a dog presenting severe nonregenerative anaemia, leukopenia and thrombocytopenia, initially testing seroreactive ...
Vinícius dos Santos Resende Rodrigues, Ellen Cristina Araújo de Medeiros, João Alfredo Biagi Camargo Neto, Igor Luiz Salardani Senhorello, Suely Regina Mogami Bomfim, Nayro Xavier de Alencar   +5 more
wiley   +1 more source

Accuracy of physical examination versus ultrasound in the detection of hepatosplenomegaly at diagnosis of pediatric leukemia

, 2013
Background: Hepatosplenomegaly (HSM) is common at diagnosis of pediatric leukemia and is diagnosed through palpation or ultrasound. We sought to determine if ultrasound was necessary.
Johnston, Donna L., Cyr, Janelle
core   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Unusual Hemodynamic Presentation of Pediatric Kikuchi‐Fujimoto Disease: Persistent Sinus Bradycardia and Vasopressor‐Dependent Hypotension

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Kikuchi‐Fujimoto disease rarely presents with vasopressor‐dependent hypotension requiring pediatric intensive care despite preserved cardiac function. This case highlights the importance of early excisional lymph node biopsy for timely diagnosis and appropriate management of children with unexplained hemodynamic instability and necrotizing ...
Abdulla Alfraij, Fatma Mothafar, Wasmi Alfadhli, Ali Ashkanani, Lujain A. Kamal, Esmail Redha, Abdulrahman Aldaithan   +6 more
wiley   +1 more source