Results 141 to 150 of about 146,077 (348)

Herbal hepatotoxicity and WHO global introspection method

Annals of Hepatology, 2013
Herbal hepatotoxicity is a rare but highly disputed disease because numerous confounding variables may complicate accurate causality assessment. Case evaluation is even more difficult when the WHO global introspection method (WHO method) is applied as ...
Rolf Teschke, M.D., Axel Eickhoff, Albrecht Wolff, Christian Frenzel, Johannes Schulze   +4 more
doaj  

Halothane hepatotoxicity [PDF]

, 1965
M.J. KIRWAN, J. W. Dundee, R.S.J. CLARKE, Ellen Siobhan Mitchell, D. W. Neill   +4 more
openalex   +1 more source

Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions

Ibrain, EarlyView.
Alzheimer's disease treatment is evolving rapidly, with emerging strategies targeting multiple disease pathways. This graphical abstract highlights the shift from traditional therapies to innovative approaches that hold promise for improving outcomes.
Tapas Kumar Mohapatra, Reena Rani Nayak, Ankit Ganeshpurkar, Prashant Tiwari, Dileep Kumar   +4 more
wiley   +1 more source

ABCG2 polymorphisms and susceptibility to ARV‐associated hepatotoxicity

Molecular Genetics & Genomic Medicine
Background The ABCG2 421C/A polymorphism contributes significantly to the distribution and absorption of antiretroviral (ARV) regimens and is associated with the undesirable side effects of efavirenz. Methods To investigate this, we examined ABCG2 34G/A (
HariOm Singh, Kishore Dhotre, Shyamveer, Ranjana Choudhari, Amita Verma, Supriya D. Mahajan, Nemat Ali   +6 more
doaj   +1 more source

Hematologic and molecular responses to ropeginterferon alfa‐2b therapy of polycythemia vera: 48‐week results from a prospective study

International Journal of Cancer, EarlyView.
What's New? Current treatment goals for polycythemia vera, a myeloproliferative neoplasm characterized by JAK2 mutations, are mainly to prevent thrombosis. While ropeginterferon alfa‐2b treatment also reduces JAK2 mutation burden, the correlation between the hematologic and molecular responses remains to be clarified.
Seug Yun Yoon, Sung‐Soo Yoon, Deok‐Hwan Yang, Gyeong‐Won Lee, Sang Kyun Sohn, Ho‐Jin Shin, Sung Hwa Bae, Chul Won Choi, Eun‐Ji Choi, June‐Won Cheong, Soo‐Mee Bang, Joon Seong Park, Suk Joong Oh, Yong Park, Young Hoon Park, Sung‐Eun Lee   +15 more
wiley   +1 more source

Evaluation of the toxicity of a substituted 2,4-thiazolidinedione moiety to isolated rat hepatocytes : relevance to glitazone toxicity [PDF]

, 2004
Troglitazone (TGZ), a 2,4 thiazolidinedione (TZD) anti-diabetic agent, has been associated with hepatotoxicity in type II diabetic patients. The mechanism of toxicity has not yet been established. However, it has been reported (Kennedy et al., 2003) that
Coxon, Geoff, Grant, M.H., Henderson, C.J., Meechan, A.J., Tettey, J.N.A.   +4 more
core  

All‐in‐one optical microfiber with an interface for MRSA in biofilms: Integrating rapid quantitative analysis and synergistic antimicrobial therapy

InfoMat, EarlyView.
Aiming at the management of MRSA biofilms, an all‐in‐one optical microfiber that integrated rapid quantitative analysis with synergistic antimicrobial therapy is developed. The prepared interfacial‐functionalized optical microfiber demonstrates the ability to detect MRSA concentrations in infection sites, enhance therapeutic efficacy, and assess ...
Pengwei Chen, Haotian Wu, Lin Liang, Tao Hu, Yunyun Huang, Zhen Lin, Hao Wu, Bai‐Ou Guan   +7 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Effect of vitamin C and quercetin treatment on the liver histopathologic profile in congenital lead exposed male rat pups [PDF]

, 2015
Introduction: Lead is one of the most important environmental pollutants due to its vast use in various industries. Lead accumulation in different organs, especially the brain, liver and kidneys can cause serious health problems.
Beheshti, N., Ganji, F., Sepehri, H.
core