Results 141 to 150 of about 79,419 (267)

Antioxidant Therapy Reverses Hepatotoxicity Induced by Microcystin-LR in a Cellular Model of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). [PDF]

J Xenobiot
Lad A, Kindle J, Hegde P, Kleer GG, Kleinhenz AL, Birbeck JA, Westrick J, Peraino NJ, Hinds TD, Purandare N, Fribley AM, Haller ST, Kennedy DJ.   +12 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

The effects of agmatine treatment on cisplatin-induced hepatotoxicity: an experimental rat study. [PDF]

Sao Paulo Med J
Yeniceri M, Senoymak MC, Bas S, Salmanoglu M, Tanoglu A.   +4 more
europepmc   +1 more source

Hepatotoxicity prediction for traditional Chinese medicine: a two-step in silico framework integrating network and machine learning approaches. [PDF]

BMC Complement Med Ther
Wu Q, Chen Z, Wang W, Wang F, Chen Z, Chi J, Huang J, Gu Y, Fang J, Cai C.   +9 more
europepmc   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

From Genotype to Functional Risk: A Multi-Omic Approach to Predicting Thiopurine and Methotrexate Co-Therapy-Induced Liver Injury. [PDF]

Pharmaceuticals (Basel)
Molnár D, Reznik E, Porrogi P.
europepmc   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

Early Detection of Nebivolol-Induced Hepatotoxicity. [PDF]

Eur J Case Rep Intern Med
Torunova AM, Kireeva VV, Kurganskii IS.
europepmc   +1 more source

Assessing the Health Impacts of Contaminants on Green Turtles (Chelonia mydas) Along the Southern Coast of Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Chemical pollutants pose a significant threat to marine ecosystems. Among these contaminants are trace elements and polycyclic aromatic hydrocarbons (PAH). Green turtles can be employed to evaluate the oceans' health due to their coastal habitats and exposure to multiple threats.
Camila Roberta da Silva Ribeiro, Andressa Maria Rorato Nascimento de Matos, Eloiza Teles Caldart, Liana Rosa, Camila Domit, Guilherme dos Santos Lima, Ana Paula Frederico Rodrigues Loureiro Bracarense   +6 more
wiley   +1 more source

Safety and Efficacy of HexaBody-DR5/DR5 in Malignant Solid Tumors: Phase 1/2a Results and Translational Insights Into Observed Hepatotoxicity. [PDF]

Clin Transl Sci
Overdijk MB, Strumane K, Plummer R, LoRusso P, Rodon Ahnert J, Banerji U, Garralda E, Calvo E, Si H, Hoevenaars N, Mortensen JT, Bosgra S, Malmberg A, Ellekilde-Pedersen M, Ramirez-Andersen T, Diamantopoulou Reiter P, Favaro E, Forssmann U, Breij ECW, Jure-Kunkel M.   +19 more
europepmc   +1 more source