Results 221 to 230 of about 30,077 (251)
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Infection involves the utilization of host nutritional resources by the pathogen. Genetic, experimental, and clinical evidence supports the critical role of iron as a focus for both pathogen attack and host defense. The molecular basis of how mammals regulate iron transport to maintain homeostasis, and in response to infection, has been well ...
Crisell, D, Talbot, N, Drakesmith, H
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Crisell, D, Talbot, N, Drakesmith, H
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2019
Hepcidin expression is determined through transcriptional regulation by systemic iron status. However, acute or chronic inflammation also increases the expression of hepcidin, which is associated with the dysregulation of iron metabolism in pathological conditions.
Yohei, Kanamori +5 more
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Hepcidin expression is determined through transcriptional regulation by systemic iron status. However, acute or chronic inflammation also increases the expression of hepcidin, which is associated with the dysregulation of iron metabolism in pathological conditions.
Yohei, Kanamori +5 more
openaire +2 more sources
Current Opinion in Hematology, 2004
Hepcidin is a recently discovered hepatic peptide that regulates intestinal iron absorption as well as maternal-fetal iron transport across the placenta. It probably also affects the release of iron from hepatic stores and from macrophages involved in the recycling of iron from hemoglobin.
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Hepcidin is a recently discovered hepatic peptide that regulates intestinal iron absorption as well as maternal-fetal iron transport across the placenta. It probably also affects the release of iron from hepatic stores and from macrophages involved in the recycling of iron from hemoglobin.
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Hepcidin and Iron in Health and Disease
Annual Review of Medicine, 2023Tomáš Ganz, Elizabeta Nemeth
exaly
Regulation of the Iron Homeostatic Hormone Hepcidin
Advances in Nutrition, 2017Veena Sangkhae, Elizabeta Nemeth
exaly
The role of the iron homeostasis mechanism is summarized in this article. Iron plays an important role in managing bodily functions such as growth and development, and makes haemoglobin, and some hormones. Hepcidin acts differently in different conditions; if the body needs more oxygen, the hepcidin levels decrease allowing iron to enter the plasma and
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Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease
Kidney International, 2009Patrick Maxwell +2 more
exaly