Results 91 to 100 of about 765 (211)

Synthesis of aryl-fused bicyclo[3.1.1]heptanes and validation as naphthyl bioisosteres. [PDF]

Nat Chem
Kerckhoffs A, Tregear M, Hernández-Lladó P, Runfola M, Shearsmith H, Frank N, Panosetti M, Squire SE, Moir L, Christensen KE, Duarte F, Davies KE, Russell AJ.   +12 more
europepmc   +1 more source

Synthesis of A-9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt. [PDF]

ACS Omega, 2022
Marvin CC, Greszler SN, Shelat BH, Voight EA.   +3 more
europepmc   +1 more source

3-Oxabicyclo[3.1.1]heptane as an Isostere of meta-Benzene. [PDF]

Angew Chem Int Ed Engl
Dibchak D, Mykhailiuk PK.
europepmc   +1 more source

Asymmetric Michael Addition of Cyanide to α,β‐Unsaturated Aldehydes Catalyzed by Diarylmethyl‐Substituted Diphenylprolinol Silyl Ethers: Thermodynamically Controlled Product Formation under Kinetic Enantioselective Catalysis

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
Asymmetric Michael addition of cyanide to α,β‐unsaturated aldehydes catalyzed by diarylmethyl‐substituted diphenylprolinol silyl ethers:Thermodynamically controlled product formation under kinetic enantioselective catalysis. Diphenylprolinol silyl ether catalyzed asymmetric Michael/1,2‐addition reaction of cyanide to α,β‐unsaturated aldehydes at high ...
Konstantinos Daskalakis, Naoki Mori, Satrajit Indu, Riku Fukami, Yujiro Hayashi   +4 more
wiley   +1 more source

Proton Relay Catalysis Enables the Synthesis of 2-Oxa- and 2-Azabicyclo[2.2.1]heptanes. [PDF]

Org Lett
Chang C, Amos SGE, Benet-Buchholz J, Kleij AW.   +3 more
europepmc   +1 more source

1,1‐and 1,2‐Diborylalkenes: Preparation and Synthetic Applications

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
In this review, we highlight recent advances in the synthesis and reactivity of 1,1‐diborylalkenes and 1,2‐diborylalkenes, along with various transformations leading to C‐C, C‐heteroatom, and multicomponent products. By providing a comprehensive and practical resource, this review aims to assist researchers in exploring the synthetic utility of 1,1 and
Jayaram Vankudoth, Maruti Mali, Fabienne Berrée   +2 more
wiley   +1 more source

Selective P450_BM3 Hydroxylation of the Spiro[3.3]heptane Core as a Route to Potential Drug Fragment Molecules. [PDF]

Org Lett
Zhang X, Zhang X, Wong LL, Robertson J.
europepmc   +1 more source

Dibenzosuberene‐Winged Polycyclic Aromatic Hydrocarbons

European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
The twisted acene 8, which features two dibenzosuberene “wings”, was prepared by the addition of a crowded aryne to a similarly “winged” cyclopentadienone. Compound 8 is chiral, and it has a high barrier to thermal racemization (ΔG‡rac = 36 kcal/mol), but it undergoes fast photochemical racemization even in ambient light.
Mingshu Xie, Xiaodong Zhang, Michael W. Johnson, Robert A. Pascal Jr   +3 more
wiley   +1 more source

Hetero[3.1.1]propellanes. [PDF]

Nat Chem
Revie RI, Dasgupta A, Biddick Y, Christensen KE, Smith RC, Anderson EA.   +5 more
europepmc   +1 more source

Umpolung Activation of Bicyclobutanes via N-Heterocyclic Carbene Catalysis. [PDF]

Angew Chem Int Ed Engl
Chang YC, Guo R, Fessard T, Lefebvre Q, Salome C, Brown MK.   +5 more
europepmc   +1 more source