Results 21 to 30 of about 3,018 (199)

Expression of Her2Neu in gastric adenocarcinoma: An institutional study

Panacea Journal of Medical Sciences, 2021
Introduction: Trastuzumab has been recently proposed as a treatment for patients with HER2-positive advanced/metastatic gastric cancer. Since most patients have inoperable disease at diagnosis, accurate assessment of HER2 status on biopsy specimens is essential to select the patients who may benefit from therapy.
Prasanta K Das, Sagarika Panda*, Manoj K Patro, Gitashree Mishra   +3 more
openaire   +1 more source

Omitting re-excision for focally positive margins after breast-conserving surgery does not impair disease-free and overall survival [PDF]

, 2017
Purpose: In contrast to other countries, the Dutch breast cancer guideline does not recommend re-excision for focally positive margins after breast-conserving surgery (BCS) in invasive tumor and does recommend whole-breast irradiation including boost. We
Baaijens, M. (Margreet), Jager, A. (Agnes), Koppert, L.B. (Linetta), Siesling, S. (Sabine), Verhoef, C. (Kees), Voogd, A.C. (Adri), Vos, E.L. (Elvira)   +6 more
core   +3 more sources

Clinicopathologic study of triple-negative breast cancer with special reference to basal-like breast cancer phenotype in a tertiary care hospital of Eastern India

Asian Journal of Medical Sciences, 2023
Background: Triple-negative breast cancer (TNBC) is defined as absent expression of estrogen receptor (ER) and progesterone receptors and human epidermal growth factor receptors (HER2neu). These cancers are associated with poor prognosis.
Rajashree Pradhan, Sajeeb Mondal , Mrinal Sikdar , Sankha Chatterjee   +3 more
doaj   +1 more source

Her2neu Amplification Associates with Co-deletion 1p/14q in Recurrent Meningiomas [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2013
Background:The current methods to predict recurrence and aggressive behaviour of meningiomas rely mainly on histological grading, histological subtype, proliferative index, as well as brain invasion. In many instances, histological grade alone fails to predict recurrence in the grade I and grade II meningiomas.
Brenda O, Hamilton, Joanne S, Sy, Joseph F, Megyesi, Lee Cyn, Ang   +3 more
openaire   +2 more sources

Immunohistochemical Expression of Her2neu in Premalignant and Malignant Lesion of Gall Bladder

Scholars Journal of Applied Medical Sciences, 2022
Purpose: To evaluate the expression of Her2-neu in benign and malignant gallbladder lesions, and to establish correlations with clinico-pathologic parameters. Materials and Methods: Retrospective and prospective analysis was conducted on formalin fixed paraffin embedded (FFPE) 154 tissue sample included Premaligant and premalignant like lesions ...
Ajay Kr .Singh, Vivek Chaudhary, Madhumati Goel, Vijay Kumar   +3 more
openaire   +1 more source

Cardiovascular safety profile of taxanes and vinca alkaloids: 30 years FDA registry experience

Open Heart, 2021
Objective Antimicrotubular agents are among the most commonly used classes of chemotherapeutic agents, but the risk of cardiovascular adverse events (CVAEs) remains unclear.
Avirup Guha, Sarju Ganatra, Brijesh Patel, Daniel Addison, Anita Deswal, Sherry-Ann Brown, Michael Fradley, Akshee Batra, Lauren A Baldassarre, Nihar Desai, Neal Weintraub, Zeeshan Hussain, Vivek Agarwala, Purvish M Parikh, Arjun Ghosh   +14 more
doaj   +1 more source

Perioperative therapy with FLOT4 significantly increases survival in patients with gastroesophageal and gastric cancer in a large real‐world cohort

International Journal of Cancer, Volume 153, Issue 3, Page 609-622, 1 August 2023., 2023
What's New In 2019, the FLOT‐4 trial established the new perioperative chemotherapy standard for patients with locally advanced gastroesophageal and gastric cancer. To date, post‐approval data remain scarce. This retrospective study verifies the real‐world efficacy of the FLOT4 protocol in the perioperative setting and demonstrates a significant ...
Christian Möhring, Adrianna Mańczak, Aliki Timotheou, Farsaneh Sadeghlar, Taotao Zhou, Robert Mahn, Malte B. Monin, Marieta Toma, Georg Feldmann, Peter Brossart, Mümtaz Köksal, Gustavo R. Sarria, Nils Sommer, Philipp Lingohr, Azin Jafari, Jörg C. Kalff, Christian P. Strassburg, Maria A. Gonzalez‐Carmona   +17 more
wiley   +1 more source

Preoperative Hormone Therapy in the Treatment of Breast Cancer: What Do We Know So Far?

Креативная хирургия и онкология, 2022
Breast cancer is the most common malignant disease in the world. One of the methods of treating breast cancer is neoadjuvant chemotherapy. Neoadjuvant chemotherapy (NCT) is now the standard of care for locally advanced breast cancer.
V. V. Vorotnikov, R. A. Pakhomova, A. V. Soinov, A. S. Gunina, I. V. Kopytich, M. G. Tsoi, S. A. Abdugafforov   +6 more
doaj   +1 more source

Histological assessment of paxgene tissue fixation and stabilization reagents [PDF]

, 2011
Within SPIDIA, an EC FP7 project aimed to improve pre analytic procedures, the PAXgene Tissue System (PAXgene), was designed to improve tissue quality for parallel molecular and morphological analysis.
Becker, K.-F. (Karl-Friedrich), Bodó, K. (Koppany), Christensen, N. (Nanna), Groelz, D. (Daniel), Jong, B.W.D. (Bas) de, Kap, Y.S. (Yolanda), Langer, R. (Robert), Oelmuller, U. (Uwe), Oosterhuis, J.W. (Wolter), Reischauer, R.D. (Robert), Riegman, P.H.J. (Peter), Slotta-Huspenina, J. (Julia), Smedts, F.M.M. (Frank), Viertler, C. (Christian), Winther, R. (Rosa), Zatloukal, K. (Kurt)   +15 more
core   +1 more source

Pattern of oestrogen, progesterone and Her2neu receptors expression in a heterogeneous carcinoma of the breast in a lactating woman [PDF]

BMJ Case Reports, 2010
Oestrogen-progestrone-Her2neu receptor status was studied in various loci/foci of heterogeneous carcinoma of the breast and its metastatic secretory component in the lymph node in a lactating woman. All the carcinoma variants were negative for the trio markers except tumour components evolved to secretory or lactating carcinoma, which showed focal ...
Mohammed, Naim, Amit, Kumar, Kavita, Gaur, Vanesa T, John   +3 more
openaire   +2 more sources