Pharmacokinetic Drug–Drug Interactions and Herb–Drug Interactions [PDF]
Pharmaceutics, 2021 Due to the growing use of herbal supplementation—ease of taking herbal supplements with therapeutics drugs (i [...]
Min-Koo Choi, Im-Sook Song
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Advances in Pharmacokinetic Mechanisms of Transporter-Mediated Herb-Drug Interactions [PDF]
Pharmaceuticals, 2022 As the use of herbs has become more popular worldwide, there are increasing reports of herb-drug interactions (HDIs) following the combination of herbs and drugs. The active components of herbs are complex and have a variety of pharmacological activities,
Jie Li +4 more
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The prevalence and predictors of herb-drug interactions among Iranian cancer patients during chemotherapy courses [PDF]
BMC Complementary Medicine and Therapies, 2023 Background The concurrent usage of herbal medicines with conventional therapies is an important concern in cancer treatment which can lead to unexpected consequences like herb-drug interactions.
Maliheh Sadat Bazrafshani +10 more
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Pharmacokinetic and pharmacodynamic herb-drug interactions—part I. Herbal medicines of the central nervous system [PDF]
PeerJ, 2023 Unlike conventional drug substances, herbal medicines are composed of a complex of biologically active compounds. Therefore, the potential occurrence of herb-drug interactions is even more probable than for drug-drug interactions.
Szilvia Czigle +4 more
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The Chinese herb Styrax triggers pharmacokinetic herb-drug interactions via inhibiting intestinal CYP3A [PDF]
Frontiers in Pharmacology, 2022 Human cytochrome P450 3A4 (hCYP3A4) is a predominant enzyme to trigger clinically relevant drug/herb-drug interactions (DDIs or HDIs). Although a number of herbal medicines have been found with strong anti-hCYP3A4 effects in vitro, the in vivo modulatory
Feng Zhang +10 more
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In Vitro Hepatic Models to Assess Herb–Drug Interactions: Approaches and Challenges [PDF]
Pharmaceuticals, 2023 A newfound appreciation for the benefits of herbal treatments has emerged in recent decades. However, herbal medication production still needs to establish standardized protocols that adhere to strict guidelines for quality assurance and risk ...
Hlengwa N. +9 more
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Expanding potential targets of herbal chemicals by node2vec based on herb–drug interactions [PDF]
Chinese Medicine, 2023 Background The identification of chemical–target interaction is key to pharmaceutical research and development, but the unclear materials basis and complex mechanisms of traditional medicine (TM) make it difficult, especially for low-content chemicals ...
Dai-yan Zhang +9 more
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Real-world Evidence of the Herb-drug Interactions. [PDF]
J Food Drug Anal, 2022 Herbal medicine (HM) is a type of medicine that uses active ingredients made from plants to treat diseases and maintain health and wellbeing. Due to its increasing worldwide usage, the possibility of HMs and conventional drugs being concurrently used is high, potentially leading to adverse events resulting from herb-drug interactions.
Pan HY +4 more
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Herb–Drug Interactions: Worlds Intersect with the Patient at the Center [PDF]
Medicines, 2021 This review examines three bodies of literature related to herb–drug interactions: case reports, clinical studies, evaluations found in six drug interaction checking resources.
Mary Beth Babos +9 more
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Cytochrome P450 and P-gp Mediated Herb-Drug Interactions and Molecular Docking Studies of Garcinol [PDF]
Membranes, 2021 Garcinol is an active constituent of Garcinia indica and Garcinia cambogia. Recent studies have proven that garcinol has anti-inflammatory, anti-cancer, and anti-oxidant activities.
Lavanya Bolla +3 more
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