Results 61 to 70 of about 44,608 (286)

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin   +14 more
wiley   +1 more source

PlantID – DNA-based identification of multiple medicinal plants in complex mixtures [PDF]

open access: yes, 2012
Background An efficient method for the identification of medicinal plant products is now a priority as the global demand increases. This study aims to develop a DNA-based method for the identification and authentication of plant species that can be ...
Bremner, Paul   +7 more
core   +2 more sources

Excipient Emulsion–Based Delivery Systems for Enhancing Carotenoid Bioavailability: Advances in Formulation and Gastrointestinal Fate

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Excipient emulsion systems improve carotenoid solubilization, protect against degradation, and enhance gastrointestinal absorption through optimized formulation and digestion behavior. ABSTRACT Carotenoids are bioactive compounds that contribute to human health through antioxidant, provitamin A, and disease‐preventive effects.
Tugce Ceyhan   +3 more
wiley   +1 more source

Drug Interaction analysis-Nigella sativa L.seed (Black Cumin) ethanolicextract on antiseizure activity of Phenobarbitone sodium

open access: yesAsian Journal of Medical Sciences, 2020
Background: Multidisciplinary therapy is gaining popularity and drug herb interactions is one of the biggest risk factor contributing to therapeutic failures or toxicities. Apart from analysis of one of such Drug-Herb combinations, this work also aims at
Lovelyn Joseph   +2 more
doaj   +1 more source

The potential roles of Nrf2/Keap1 signaling in anticancer drug interactions

open access: yesCurrent Research in Pharmacology and Drug Discovery, 2021
Nuclear factor (erythroid-derived 2)-related factor 2 (Nrf2), together with its suppressive binding partner Kelch-like ECH-associated protein 1 (Keap1), regulates cellular antioxidant response and drug metabolism. The roles of Nrf2/Keap1 signaling in the
Jingya Wang   +5 more
doaj   +1 more source

How safe are herbal products? [PDF]

open access: yes, 2000
In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core  

Hepatitis induced by noni juice from Morinda citrifolia: A rare cause of hepatotoxicity or the tip of the iceberg? [PDF]

open access: yes, 2006
A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-la for 6 weeks.
Diebold, J.   +3 more
core   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

open access: yesAdvanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova   +4 more
wiley   +1 more source

Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) [PDF]

open access: yes, 2012
Many active components of herbal products are small organic anions, and organic anion transporters were previously demonstrated to be a potential site of drug-drug interactions.
Sweet, Douglas H., Wang, Li
core   +3 more sources

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang   +10 more
wiley   +1 more source

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