Results 161 to 170 of about 2,262,792 (340)

Current status of herbal and their future perspectives [PDF]

, 2007
Traditional medicine is the synthesis of therapeutic experience of generations of practicing physicians of indigenous systems of medicine. Throughout the history of mankind, many infectious diseases have been treated with herbals.
Ponnampalam Gopalakrishnakone, Ramar Perumal R. Samy   +1 more
core   +1 more source

A Phase 1 Open‐Label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Intranasal Dose of Zavegepant in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Zavegepant is the only calcitonin gene‐related peptide antagonist approved as a nasal spray in the United States for acute treatment of migraine in adults with or without aura. This Phase 1, open‐label study evaluated the pharmacokinetics, safety, and tolerability of a single intranasal dose of zavegepant 10 mg in 12 healthy Chinese adults ...
Qiong Wei, Jufang Wu, Yangyi Dai, Jiaye Lin, Beikang Ge, Yanhui Sun, Jing Zhang, Jing Wang, Chen Li, Ding Ding, Jing Liu, Mohamed H. Shahin   +11 more
wiley   +1 more source

Herbal medicine use and its impact on glycemic control among diabetes patients at governmental hospitals in Debre Berhan, Ethiopia: A cross-sectional study

Metabolism Open
Background: Diabetes mellitus (DM) is a major health concern worldwide. Diabetes patients are increasingly using herbal medicine (HM) without seeking advice from their healthcare providers.
Girma Deshimo Lema, Enguday Demeke Gebeyaw, Zena Admasu Yferu, Seife Feleke Mulatu, Asrat Berihun Dagnaw, Getachew Bizuneh Aydagnuhm, Esubalew Amanu Ayicheh   +6 more
doaj   +1 more source

Comprehensive review on herbal medicine for energy intake suppression [PDF]

, 2010
Nancy Dewi Yuliana, Muhammad Jahangir, Henrie Korthout, Young Hae Choi, Hye Kyong Kim, Robert Verpoorte   +5 more
openalex   +1 more source

Prospects and Challenges of Medicinal Plants Conservation and\ud Traditional Medicine in Tanzania [PDF]

, 2013
A qualitative study was carried to assess prospects and challenges of medicinal plants conservation and\ud traditional medicine in Tanzania. The study shows that TRM and medicinal have great prospects in healthcare\ud delivery worldwide.
Kayombo, Edmund J, Mahunnah, Rogasian L A, Uiso, Febronia C   +2 more
core  

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Herbal and Holistic Medicine in Latin America [PDF]

, 2014
A variety of herbal and holistic remedies were used in pre-Columbian cultures, especially in Aztec and Incan cultures. Many different herbs were used to provide medical attention to patients directly, while other herbs were used to supplement shaman[1 ...
Lyle, William H.
core   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

An Evaluation of the Drug Interaction Potential of Encorafenib in Combination With Binimetinib Using the Inje Cocktail in Patients With Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
A clinical drug–drug interaction (DDI) study was designed to evaluate the effect of single and multiple oral doses of encorafenib on the single oral dose pharmacokinetics (PK) of the cytochrome P450 (CYP) enzyme probe substrates, losartan (CYP2C9), midazolam (CYP3A4), caffeine (CYP1A2), omeprazole (CYP2C19), and dextromethorphan (CYP2D6) administered ...
Joseph Piscitelli, Micaela B. Reddy, Lance Wollenberg, Laurence Del Frari, Jason Gong, Kyle Matschke, Jason H. Williams   +6 more
wiley   +1 more source