Results 171 to 180 of about 245,806 (333)

In‐Silico Exploration of the StreptomeDB Database for Potential Irreversible DprE1 Inhibitors toward Antitubercular Treatment

open access: yesChemistryOpen, EarlyView.
StreptomeDB‐derived nitro compounds are screened against Mycobacterium tuberculosis decaprenylphosphoryl‐D‐riboseoxidase (DprE1) . Covalent docking, molecular dynamics simulations, and molecularmechanics/generalized Born surface area analyses identify hydroxythaxtomin and lajollamycin B as potent DprE1 inhibitors, surpassing the reference PBTZ169 in ...
Doaa G. M. Mahmoud   +4 more
wiley   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

open access: yesChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges   +15 more
wiley   +1 more source

Herbicides in Use: Current Status and Perspectives in the Different Biogeographic Regions of Europe. [PDF]

open access: yesJ Agric Food Chem
Synowiec A   +24 more
europepmc   +1 more source

The missing woodland story: Implications of 1700 years of stand‐scale change on ‘naturalness’ and managing remnant broadleaved woodlands

open access: yesPeople and Nature, EarlyView.
Abstract Longer‐term perspectives—equivalent to the lifespans of long‐lived trees—are required to fully inform perceptions of ‘naturalness’ used in woodland conservation and management. Stand‐scale dynamics of an old growth temperate woodland are reconstructed using palaeoecological data.
Annabel Everard   +4 more
wiley   +1 more source

Understanding smallholder decision‐making to increase farm tree diversity: Enablers and barriers for forest landscape restoration in Western Kenya

open access: yesPeople and Nature, EarlyView.
Abstract Integrating diverse trees and shrubs (hereafter ‘trees’) in agricultural landscapes has emerged as a crucial nature‐based solution to the triple challenge of biodiversity loss, climate change and food security. The potential benefits of on‐farm trees for both people and nature, however, are often constrained by inadequate consideration of ...
Ennia Bosshard   +6 more
wiley   +1 more source

Generating Broad-Spectrum Resistance to ALS-Inhibiting Herbicides in Rice by CRISPR/Cas9-Mediated NHEJ. [PDF]

open access: yesRice (N Y)
Ouyang C   +10 more
europepmc   +1 more source

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