Results 201 to 210 of about 269,395 (254)

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

Maternal Obesity Doubles the Risk of Preeclampsia and Eclampsia: Post-COVID Changes in a Brazilian Cohort of 2.3 Million Hospitalizations. [PDF]

Pathophysiology
de Souza PVF, Salgado-Ramos MC, Quadros JP, Moraes JC, Santos da Silva DL, da Camara AO, Cardoso RC, Freitas HR.   +7 more
europepmc   +1 more source

Targeting Renal IGFBP7 With Tetrahedral Framework Nucleic Acid‐Delivered siRNA Alleviates Acute Kidney Injury

iNew Medicine, EarlyView.
A tFNA‐based siRNA delivery system targeting IGFBP7 effectively silences IGFBP7 expression and attenuates renal dysfunction, tubular injury, and cell death in both septic (CLP) and ischemic (I/R) murine models of acute kidney injury. ABSTRACT Objective Acute kidney injury (AKI) is a common and serious clinical condition, yet effective targeted ...
Shao‐qi Wu, Ying‐ying Gao, Meng‐yi Jia, Yu‐Hao Liu, Qian Zhou, Dong Liu, Yu Ren, Yu‐jie Liu, Feng‐he Li, Ya‐ru Yang, Jie Wang, Jia‐gen Wen   +11 more
wiley   +1 more source

Patient and staff experiences of a community-based diagnostic clinic for chronic eye conditions: Qualitative analysis. [PDF]

Eye (Lond)
Ramsay AIG, Adesanya J, Bazo-Alvarez JC, Baker H, Cammack J, Clarke CS, Elphinstone H, Alarcon Garavito G, Khaw SPT, Kumpunen S, Mills G, Muhundhakumar D, Napier S, Ndwandwe S, Scully P, Symons A, Jayaram H, Sivaprasad S, Foster PJ, Fulop NJ, HERCULES research consortium.   +20 more
europepmc   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

First in situ observations of the goblin shark Mitsukurina owstoni. [PDF]

J Fish Biol
Judah AB, Jamieson AJ, Bingo SRD, Cundy ME, Ebert DA, Auscavitch S, Carlson HK, Cunanan TNG, Sims HB, Putts M.   +9 more
europepmc   +1 more source

HMGB2 Impacts Cisplatin-Induced DNA Adduct Processing in Chemoresistant Ovarian Cancer Cells. [PDF]

Genes (Basel)
Huynh V, Wang G, Vasquez KM.
europepmc   +1 more source

Quantifying Effects of OM–Cation Interactions on Mid‐Infrared FTIR Absorption Spectra of Polygalacturonic Acid

Journal of Plant Nutrition and Soil Science, EarlyView.
The composition of organic matter (OM) was explained by effects of OM–cation interactions using polygalacturonic acid (PGA) as model substance. These effects were analyzed by COO− absorption bands in mid‐FTIR spectra. The change in intensity and wavenumber ranges of COO− bands in FTIR was quantified.
Ruth H. Ellerbrock, Nisha Bhattarai, Horst H. Gerke   +2 more
wiley   +1 more source

Cohort profile: Design and methods for Project HERCULES (Healthcare Exemplar for Recovery from COVID 19 Using Linear Examination Systems): Multi-disciplinary implementation and evaluation of an asynchronous review clinic in NHS eye-care services. [PDF]

PLoS One
Muhundhakumar D, Clarke CS, Mills G, Ramsay AIG, Sailer K, Scully P, Wilson D, Fu DJ, Ndwandwe S, Pachilova R, Symons A, Napier S, Adesanya J, Gazzard G, Hamilton R, Wilson J, Webster P, Khaw PT, Sivaprasad S, Jayaram H, Foster PJ, HERCULES Consortium.   +21 more
europepmc   +1 more source

Composition and functionalities of peanut protein concentrates using ethanol as a defatted solvent and a precipitating agent

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Defatted solids (DSs) from vegetable oil extraction represent valuable feedstocks for producing protein concentrates with tailored functional properties. In the present study, using peanut protein concentrates obtained from press cakes defatted with ethanol (DSEt) or hexane (DSHx), we aimed to evaluate ethanol as a green solvent for
Paloma Jamily Cristina Magalhães, Luiza Cardoso Stumm, Paola de Cássia Franco Visioli, Keila Kazue Aracava, Rafaela Torrezan Privatti, Maria Carolina Capellini, Silvana Marina Piccoli Pugine, Daniel Gonçalves, Christianne Elisabete da Costa Rodrigues   +8 more
wiley   +1 more source