ABSTRACT N6‐methyladenosine (m6A) plays a critical role in osteoarthritis (OA) pathogenesis. This study investigates the role of the m6A reader insulin‐like growth factor 2 mRNA‐binding protein 3 (IGF2BP3) in OA progression. OA models were established in vivo through destabilization of the medial meniscus (DMM) surgery in mice and in vitro by ...
Xing‐Shi Yuan +8 more
wiley +1 more source
RNAi of the electron transport chain <i>ATPsynβL</i> in glutamate neurons protects against age-related intestinal barrier dysfunction. [PDF]
Longenecker M +4 more
europepmc +1 more source
Abstract Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor originating from calcitonin producing C‐cells and accounts for 1–5% of thyroid cancers. Total thyroidectomy is curative in localized disease (N0), whereas lymph node metastases (N1) are associated with poorer prognosis.
Anna Citarella +24 more
wiley +1 more source
Correction: Salviaflaside in water-soluble fraction of heated water extracted from defatted <i>Perilla frutescens</i> Britton var. <i>japonica</i> Hara seed residue suppresses osteoclast differentiation. [PDF]
Asano H, Nishimoto S.
europepmc +1 more source
Field inoculation with arbuscular mycorrhizal fungi (AMF) offers a promising route to improve sustainable agriculture and food production, yet results are often variable. We investigated the mycorrhizal growth response of maize and wheat varieties recommended for farmers and found substantial variation under greenhouse conditions.
Ido Rog +5 more
wiley +1 more source
Engineering of a Carbonic Anhydrase from <i>Hydrogenimonas thermophila</i> Through Fusion Tags and Surface Mutagenesis Enhances Solubility While Revealing Stability-Function Relationships. [PDF]
Manyumwa CV, Jers C, Mijakovic I.
europepmc +1 more source
Improved Step-by-Step qPCR Method for Absolute Telomere Length Measurement. [PDF]
Arshinova ES +4 more
europepmc +1 more source
Tracing stratospheric transport using subannual plutonium-239 fallout in polar ice cores. [PDF]
Shin J +6 more
europepmc +1 more source
Permanent seed brachytherapy for prostate cancer: Monotherapy, combined, and salvage approaches remain effective and well-tolerated options. [PDF]
Esteves SCB +6 more
europepmc +1 more source

