Results 211 to 220 of about 1,118,282 (282)

Attentional, Affective, and Cognitive Responses to the Food and Drug Administration's "The Real Cost" Youth Cigarette and E-Cigarette Prevention Campaigns Among Young Adults. [PDF]

Am J Prev Med
Weiger C, Tfayli D, Ibrahim M, McKneely JA, Vigorita M, Peterson EB, Moran MB.   +6 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

ZFP148 is a transcriptional repressor of cytolytic effector CD8⁺ T cell differentiation. [PDF]

Nat Immunol
Xiao T, Chen X, Song NJ, Brown RJ, Ma A, Mandula JK, Yousif A, Wang Y, Le MQM, Li J, Gao F, Weaver B, Chen HY, Lay FY, Sundi D, Velegraki M, Weltge P, Merchant JL, Rubinstein MP, Oestreich KJ, Lio CJ, Ghoneim HE, Li X, Theodorescu D, Xin G, Ma Q, Cui W, Li Z.   +27 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Introduction to the Supplement. [PDF]

Muscle Nerve
Gwathmey KG, Apple S.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Community Disassembly in a Fragmented Tropical Landscape Driven by Both Deterministic and Stochastic Processes. [PDF]

Ecol Evol
Azhar I, Sihaloho HF, Struebig MJ, Senawi J, Rossiter SJ, Phillips CD, Kingston T.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Psychological Factors Related to Social Exclusion of Hikikomori (Prolonged Social Withdrawal) Individuals by Local Residents. [PDF]

Yonago Acta Med
Takeda S, Ota M, Fujii Y, Fujiyoshi K, Hiroe J, Hiroe S, Hirosawa M, Kawakami M, Kikumoto R, Maezawa Y, Morimoto K, Nagami Y, Takashima C, Tazumi H, Yamamoto M, Komoda R.   +15 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source