Results 91 to 100 of about 197,953 (330)

Mitigating Disparity in Health-care Resources Between Countries for Management of Hereditary Angioedema

Clinical reviews in allergy and immunology, 2021
Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of skin and mucosal edema. The main treatment goal is to enable a “normal life” for all patients.
A. Jindal, A. Reshef, Hilary Longhurst, Werner Stephen Konrad Emel Marcus Markus Laurence Anette Aberer Betchel Bork Aygören-Pürsün Maurer Magerl B, W. Aberer, Stephen Betchel, K. Bork, E. Aygören‐Pürsün, M. Maurer, M. Magerl, L. Bouillet, A. Bygum, T. Caballero, M. Cancian, H. Farkas, V. Grivcheva-Panovska, A. Grumach, O. Gulbahar, M. Hide, A. Jindal, Surjit Singh, H. Kang, A. Reshef, A. Kessel, Hilary Longhurst, K. Lindsay, A. Jordan, R. Ameratunga, W. Lumry, J. Bernstein, T. Craig, M. Riedl, D. Levy, A. Malbrán, A. Germenis, F. Psarros, M. Stobiecki, G. Porębski, A. Valerieva, Fiona Wardman, Youjia Zhong, C. Weber   +41 more
semanticscholar   +1 more source

Hereditary angioedema as a cause of recurrent abdominal pain in a pediatric patient with Crohn's disease

JPGN Reports, EarlyView.
Abstract Hereditary angioedema (HAE) is a rare genetic condition caused by deficient or dysfunctional C1 inhibitor protein (C1INH) resulting in episodic angioedema of the skin, upper airway, and gastrointestinal tract. HAE most often presents within the first two decades of life and may cause severe abdominal pain, nausea, diarrhea, and emesis, making ...
Stephanie L. Rager, Paula J. Busse, Joesph A. Picoraro   +2 more
wiley   +1 more source

Long‐Term Real‐World Effectiveness of Rupatadine in Chronic Urticaria: A Retrospective Observational Study

JEADV Clinical Practice, EarlyView.
This retrospective observational study analyzed a cohort of chronic urticaria (CU) patients to provide insight into the clinical practice of CU with second‐generation antihistamines (SgAHs) and to evaluate the long‐term real‐world effectiveness of rupatadine in CU. Patients with chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU)
A. M. Giménez‐Arnau, C. Romero, M. March, A. Tomas, I. Izquierdo, R. M. Pujol   +5 more
wiley   +1 more source

Development of a disease-specific quality of life questionnaire for adult patients with hereditary angioedema due to C1 inhibitor deficiency (HAE-QoL): Spanish multi-centre research project [PDF]

, 2012
BACKGROUND: There is a need for a disease-specific instrument for assessing health-related quality of life in adults with hereditary angioedema due to C1 inhibitor deficiency, a rare, disabling and life-threatening disease.
Carmen Gómez-Traseira, Carmen Marcos, Concepción López-Serrano, Dolores Hernández de Rojas, Eduardo Remor, Javier Contreras, Mar Guilarte, María Rubio, Miguel Tejedor-Alonso, Nieves Prior, Rosario Cabañas, Stefan Cimbollek, Teresa Caballero, Teresa González-Quevedo, Victoria Cardona, Ángel Campos   +15 more
core   +1 more source

Effect of COVID-19 on hereditary angioedema activity and quality of life.

Allergy and Asthma Proceedings, 2021
Background: The demonstration that severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) enters the cell via the angiotensin-converting enzyme 2 receptor has raised concerns that, in hereditary angioedema (HAE), a disease characterized by ...
Ozge Can Bostan, G. Tuncay, E. Damadoğlu, G. Karakaya, A. Kalyoncu   +4 more
semanticscholar   +1 more source

Atopic Comorbidities Associated With Chronic Spontaneous Urticaria: A Case‐Control Analysis of the All of Us Research Program

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Chronic spontaneous urticaria (CSU) is a mast cell‐driven condition defined by recurrent wheals and/or angioedema lasting over 6 weeks without an identifiable trigger. Though CSU is known to co‐occur with atopic diseases and share Th2‐dominant immunologic pathways, prior studies have not adequately addressed these relationships in ...
Julian A. Cortes, Nana Ama Adjei‐Frimpong, Savannah K. Fakhouri, Francesco Delacqua, Reid Oldenburg   +4 more
wiley   +1 more source

A narrative review of recent literature of the quality of life in hereditary angioedema patients

World Allergy Organization Journal, 2023
Hereditary angioedema (HAE) is a rare disorder that causes unpredictable and debilitating cutaneous and submucosal edema and can lead to death. HAE can impair patients' ability to perform daily activities, proportional to pain severity, with patients ...
Herberto José Chong-Neto
doaj   +1 more source

Impact of lanadelumab in hereditary angioedema: a case series of 12 patients in Canada

Allergy, Asthma & Clinical Immunology, 2021
Background Hereditary angioedema (HAE) is a rare autosomal dominant disease resulting in recurring episodes of swelling, leading to considerable patient morbidity and mortality.
Aled Iaboni, A. Kanani, G. Lacuesta, Christine H Song, Manstein Kan, S. Betschel   +5 more
semanticscholar   +1 more source

Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD

The Laryngoscope, EarlyView.
The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne, William Eschenbacher, Ryan Stepp, Larry Borish   +3 more
wiley   +1 more source

Burden of Illness in Hereditary Angioedema:A Conceptual Model [PDF]

, 2015
The objective of the Hereditary Angioedema Burden of Illness Study in Europe was to assess the real-world experience of hereditary angioedema (HAE) from the patient perspective.
Aygören-Pürsün, Emel, Beusterien, Kathleen, Boysen, Henrik B, Bygum, Anette, Caballero, Teresa, Hautamaki, Emily, Sisic, Zlatko, Wait, Suzanne   +7 more
core   +2 more sources