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Impact of Dental Procedures on Hereditary Angioedema Attacks: An Exploratory Observational Study. [PDF]
Oral Health Prev DentNadasan V +3 more
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New England Journal of Medicine, 2020
Hereditary angioedema is a disorder characterized by recurrent episodes of severe swelling (angioedema). The most common areas of the body to develop swelling are the limbs, face, intestinal tract, and airway. Minor trauma or stress may trigger an attack,
Sandra C Christiansen, Paula J. Busse
semanticscholar +6 more sources
Hereditary angioedema is a disorder characterized by recurrent episodes of severe swelling (angioedema). The most common areas of the body to develop swelling are the limbs, face, intestinal tract, and airway. Minor trauma or stress may trigger an attack,
Sandra C Christiansen, Paula J. Busse
semanticscholar +6 more sources
Immunology and Allergy Clinics of North America, 2023 Hereditary angioedema (HAE) is a rare autosomal dominant genetic disorder that usual results from a decreased level of functional C1-INH and clinically manifests with intermittent attacks of swelling of the subcutaneous tissue or submucosal layers of the respiratory or gastrointestinal tracts.
R. G. Wilkerson, Joseph J Moellman
semanticscholar +6 more sources
Guidelines for management of hereditary angioedema: What is new? What is missing?
Allergy and Asthma Proceedings, 2022Background: Hereditary angioedema is an autosomal dominant disease that presents with recurrent episodic swelling of the submucosal and/or subcutaneous tissues of the cutaneous, gastrointestinal, and respiratory systems.
C. Radojicic
semanticscholar +1 more source
Annals of Emergency Medicine, 1988
Although the condition is rare, patients with hereditary angioedema often present because of abdominal pain or airway compromise. A 27-year-old woman presented to the emergency department in acute abdominal distress. Identification of the disease in this patient allowed for proper management and avoidance of invasive procedures.
G P, Moore, W T, Hurley, S A, Pace
openaire +2 more sources
Although the condition is rare, patients with hereditary angioedema often present because of abdominal pain or airway compromise. A 27-year-old woman presented to the emergency department in acute abdominal distress. Identification of the disease in this patient allowed for proper management and avoidance of invasive procedures.
G P, Moore, W T, Hurley, S A, Pace
openaire +2 more sources
CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema.
New England Journal of MedicineBACKGROUND Hereditary angioedema is a rare genetic disease that leads to severe and unpredictable swelling attacks. NTLA-2002 is an in vivo gene-editing therapy based on clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated
Hilary Longhurst +22 more
semanticscholar +1 more source
Current Opinion in Hematology, 2005
Hereditary angioedema is an autosomal-dominant deficiency of C1 inhibitor--a serpin inhibitor of kallikrein, C1r, C1s, factor XII, and plasmin. Quantitative or qualitative deficiency of C1 inhibitor leads to the generation of vasoactive mediators, most likely bradykinin.
openaire +4 more sources
Hereditary angioedema is an autosomal-dominant deficiency of C1 inhibitor--a serpin inhibitor of kallikrein, C1r, C1s, factor XII, and plasmin. Quantitative or qualitative deficiency of C1 inhibitor leads to the generation of vasoactive mediators, most likely bradykinin.
openaire +4 more sources
Oral Sebetralstat for On-Demand Treatment of Hereditary Angioedema Attacks.
New England Journal of MedicineBACKGROUND Approved on-demand treatments for hereditary angioedema attacks need to be administered parenterally, a route of administration that is associated with delays in treatment or withholding of therapy.
Marc A. Riedl +30 more
semanticscholar +1 more source