Results 41 to 50 of about 3,222,626 (259)

Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies [PDF]

, 2005
Includes bibliographical references.Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa.
Holm, Hannes
core   +1 more source

Serum Iron Level and 10-Year Survival after Melanoma

Biomedicines, 2022
The malignant melanoma of the skin is a very aggressive tumor. The determination of prognostic biomarkers is important for the early detection of recurrence, and for the enrollment of the patients into different treatment regimens.
Karolina Rowińska, Piotr Baszuk, Emilia Rogoża-Janiszewska, Jakub Deptuła, Wojciech Marciniak, Róża Derkacz, Marcin Lener, Cezary Cybulski, Magdalena Kiedrowicz, Magdalena Boer, Mariola Marchlewicz, Tadeusz Dębniak, Jan Lubiński   +12 more
doaj   +1 more source

Public support for healthcare-mediated disclosure of hereditary cancer risk information : Results from a population-based survey in Sweden

, 2020
Background: Targeted surveillance of at-risk individuals in families with increased risk of hereditary cancer is an effective prevention strategy if relatives are identified, informed and enrolled in screening programs.
Hellquist, BN, Melin, Beatrice,, Andersson, A, Hawranek, C, Hellquist, Barbro Numan, Hawranek, C., Hawranek, Carolina,, Numan Hellquist, Barbro, Grill, K, Öfverholm, Anna, Grill, Kalle,, Rosen, A., Hajdarevic, S, Hajdarevic, S., Andersson, Andreas,, Ofverholm, A, Rosén, Anna, Ehrencrona, H., Andersson, Andreas, Ehrencrona, Hans, Öfverholm, Anna,, Melin, B., Andersson, A., Grill, Kalle, Tham, Emma, Melin, Beatrice, Melin, B,, Ehrencrona, H, Rosén, Anna,, Hajdarevic, Senada,, Grill, K., Tham, E., Hajdarevic, Senada, Hawranek, Carolina, Rosen, A, Numan Hellquist, Barbro,, Hellquist, B. N., Tham, E,   +37 more
core   +1 more source

An oncologist-based model of cancer genetic counselling for hereditary breast and ovarian cancer [PDF]

, 2004
Background: We describe a multistep model of cancer genetic counselling designed to promote awareness, and disease surveillance and preventive measures for hereditary and familial breast and ovarian cancer.
SILINGARDI, Vittorio, CORTESI L., RICEVUTO E., CAPUANO I., FEDERICO M., VENUTA S., CONTEGIACOMO A., Capuano I, Cortesi L, Contegiacomo A, Marchetti P, Pensabene M, MARCHETTI, PAOLO, Ricevuto E, SILINGARDI V, Cianci G, BARBIERI, Viola, TURCHETTI, DANIELA, Venuta S, FEDERICO M, PENSABENE M., TAUCHMANOVA L., FEDERICO, Massimo, CIANCI G., Tauchmanova L, ITALIAN NETWORK ON HEREDITARY BREAST CANCER, BARBIERI V, Turchetti D, MARCHETTI P., ON BEHALF OF THE ITALIAN NETWORK ON HEREDITARY BREAST CANCER, SILINGARDI V.   +30 more
core   +1 more source

Identification of novel germline mutations in hereditary colorectal cancer patients and characterization of somatic alterations in their tumors [PDF]

, 2008
Colorectal cancer has been reported as the third leading cause of cancer related death in the world. About 5-10% of colorectal cancers are due to an inherited predisposition.
Zhang, Jian
core   +1 more source

Development and early‐stage evaluation of a patient portal to enhance familial communication about hereditary cancer susceptibility testing: A patient‐driven approach

Health Expectations, 2023
Introduction Genetic testing for hereditary cancer syndromes (HCSs) can improve health outcomes through cancer risk mitigation strategies. Effective communication between tested individuals and their family members is key to reducing the hereditary ...
Samantha Pollard, Deirdre Weymann, Rosalie Loewen, Jennifer Nuk, Sophie Sun, Kasmintan A. Schrader, Chiquita Hessels, Dean A. Regier   +7 more
doaj   +1 more source

TP53 germline testing and hereditary cancer: how somatic events and clinical criteria affect variant detection rate

Genome Medicine
Background Germline heterozygous pathogenic variants (PVs) in TP53 cause Li-Fraumeni syndrome (LFS), a condition associated with increased risk of multiple tumor types. As the associated cancer risks were refined over time, clinical criteria also evolved
Paula Rofes, Carmen Castillo-Manzano, Mireia Menéndez, Álex Teulé, Sílvia Iglesias, Elisabet Munté, Mireia Ramos-Muntada, Carolina Gómez, Eva Tornero, Esther Darder, Eva Montes, Laura Valle, Gabriel Capellá, Marta Pineda, Joan Brunet, Lidia Feliubadaló, Jesús del Valle, Conxi Lázaro   +17 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Considerations on diagnosis and surveillance measures of PTEN hamartoma tumor syndrome: clinical and genetic study in a series of Spanish patients

Orphanet Journal of Rare Diseases, 2022
Background The limited knowledge about the PTEN hamartoma tumor syndrome (PHTS) makes its diagnosis a challenging task. We aimed to define the clinical and genetic characteristics of this syndrome in the Spanish population and to identify new genes ...
Laura Pena-Couso, María Ercibengoa, Fátima Mercadillo, David Gómez-Sánchez, Lucía Inglada-Pérez, María Santos, Javier Lanillos, David Gutiérrez-Abad, Almudena Hernández, Pablo Carbonell, Rocío Letón, Mercedes Robledo, Cristina Rodríguez-Antona, José Perea, Miguel Urioste, PHTS Working Group   +15 more
doaj   +1 more source