Results 121 to 130 of about 427,242 (236)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Successful Pregnancy Outcome in a Patient with Recurrent Miscarriage Due to PCOS Complicated by Hereditary Protein C Deficiency. [PDF]

Int J Womens Health
Qiu L, Zhong M, Tu Y, Mo H, Li L.
europepmc   +1 more source

Recurrent transfusion‐related acute lung injury after fresh frozen plasma in a patient with hereditary factor V deficiency [PDF]

, 2008
Alvaro C. Laga, Jonathan D. Kurtis, Joseph Sweeney   +2 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Genetic tumor syndromes in female cancer: insights into inherited cancer predisposition and clinical implications. [PDF]

Arch Gynecol Obstet
Krückel A, Gocke J, Hörner M, Keller K, Müller C, Brückner L, Heindl F, Hack CC, Beckmann MW, Amann N.   +9 more
europepmc   +1 more source

Interplay between hereditary and acquired factors determines the neutrophil counts in older individuals

, 2023
Marie-France Gagnon, Sylvie Provost, Maxine Sun, Sami Ayachi, Manuel Buscarlet, Luigina Mollica, Natasha Szuber, Marie‐Pierre Dubé, Lambert Busque   +8 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Skin cancer risk in hereditary mixed cancer syndromes. [PDF]

Hered Cancer Clin Pract
Nikkola V, Alakoski A, Mecklin JP, Seppälä TT, Nikkola J, Schrader K.   +5 more
europepmc   +1 more source

Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer [PDF]

, 2010
Stephen G. Chun, Nelson S. Yee
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source