Results 161 to 170 of about 14,685,767 (350)

Factors associated with genetic testing distress in patients tested for Lynch Syndrome or Hereditary Breast and Ovarian Cancer Syndrome [PDF]

, 2011
Margery Rosenblatt, Monica Dandapani, Rowena Mercado, Judy E. Garber, Sapna Syngal, Elena M. Stoffel   +5 more
openalex   +1 more source

Hereditary Arrhythmias

Ventricular tachyarrhythmias (ventricular tachycardia [VT] or ventricular fibrillation [VF]) are associated with syncope, aborted cardiac arrest (ACA) or sudden cardiac death (SCD).
Barsheshet, Alon, Goldenberg, Ido, Huang, David T   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Factor XII–independent activation of the bradykinin-forming cascade: Implications for the pathogenesis of hereditary angioedema types I and II [PDF]

, 2013
Kusumam Joseph, Baby G. Tholanikunnel, Anette Bygum, Berhane Ghebrehiwet, Allen P. Kaplan   +4 more
openalex   +1 more source

Decision letter for "Factors influencing genetic counseling and testing for hereditary breast and ovarian cancer syndrome in a large US health care system"

, 2021

openalex   +1 more source

Hereditary and non-hereditary factors affecting starch content in potato tubers

, 2016
This literature review relates to the starch which is presented in potato tubers, and hereditary and non-hereditary factors that influence content of the starch. At the beginning of the work, the attention is paid to the potatoes itself, especially their
Malá, Lucie
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Willingness of Chinese Breast Cancer Patients for Their Children to Undergo <i>BRCA1/2</i> Genetic Testing and Associated Factors. [PDF]

Int J Womens Health
Yu X, Wu M, Liu L, Zhang C.
europepmc   +1 more source

Hereditary ataxia; a survey of certain clinical, pathologic and genetic features with linkage data on five additional hereditary factors.

, 1951
John W. Schut
openalex  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source