Results 211 to 220 of about 429,052 (284)

Amyloidogenic phenotypical variation affects post-transplant outcome of hereditary transthyretin amyloidosis: a retrospective study. [PDF]

eGastroenterology
Wilczek HE, Tranäng M, Coelho T, Ericzon BG.   +3 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Concept of neuroendocrine neoplasms of all organs with a focus on grading, subtyping. [PDF]

Virchows Arch
Kasajima A, Perren A, Klöppel G.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Prognostic Value of MicroRNA Profiles in Septic Patients with Rare Hereditary Anemias: Insights from a Longitudinal Cohort Study. [PDF]

Int J Gen Med
AlMoshary M, Qushmaq NA, Elgujja A, Alamoudi AM, AlQahtani MA, Bugshan H, Antony MV, Alshahrani F.   +7 more
europepmc   +1 more source

Prevalence of risk factors associated with breast cancer in hereditary breast and ovarian cancer syndrome in Latin American patients

Maria Paula Amaya Rojas, Gustavo Alfonso Díaz Muñoz, Angela Maria Castañeda Gomez, Juan Camilo Chaparro Daza, Juan Diego Angulo Arriola, Daniela Montoya Ossa   +5 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Recurrent pregnancy loss: systematic review and meta-analysis of overall prevalence and the distribution of major etiological categories. [PDF]

Front Med (Lausanne)
Carvalho T, Ângelo-Dias M, Moutinho F, Serra SS, Costa T, Martins JP, Duarte GS, Lima J.   +7 more
europepmc   +1 more source

Hereditary Endometrial Cancer: Lynch Syndrome, Mismatch Repair Deficiency, and Emerging Genetic Predispositions-A Comprehensive Review with Clinical and Laboratory Guidelines. [PDF]

Int J Mol Sci
Kluk A, Gryczka H, Braszka M, Ałtyn R, Markiewicz H, Ślężak JK, Dwojak E, Czerniak J, Zieliński P, Płachno BJ, Dobosz P.   +10 more
europepmc   +1 more source

Epidemiology of Irritable Bowel Syndrome - hereditary and non-hereditary factors

, 2018
Rasmus Waehrens
openalex   +1 more source